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Does exposure to indoor allergens contribute to the development of asthma and allergy?

Does exposure to indoor allergens contribute to the development of asthma and allergy?
Does exposure to indoor allergens contribute to the development of asthma and allergy?
Common indoor allergens include house dust mite, cockroach, animal dander, and certain molds. In genetically susceptible children, exposure to these indoor allergens during the critical postnatal period may lead to sensitization in early childhood. Consistent evidence indicates that children sensitized to common indoor allergens are at several-fold higher risk of asthma and allergy. Due to conflicting evidence from prospective studies, some doubt remains regarding a direct and dose-response relationship between exposure and development of asthma. However, in recent years, evidence has accumulated that exposure to indoor allergen causes asthma and allergy, but this effect may depend on dose and type of allergen as well as the underlying genetic susceptibility of the child.
asthma, allergen, prevention, environment, allergy, atopy
1529-7322
49-55
Arshad, S. Hasan
917e246d-2e60-472f-8d30-94b01ef28958
Arshad, S. Hasan
917e246d-2e60-472f-8d30-94b01ef28958

Arshad, S. Hasan (2009) Does exposure to indoor allergens contribute to the development of asthma and allergy? Current Allergy and Asthma Reports, 10 (1), 49-55. (doi:10.1007/s11882-009-0082-6). (PMID:20425514)

Record type: Article

Abstract

Common indoor allergens include house dust mite, cockroach, animal dander, and certain molds. In genetically susceptible children, exposure to these indoor allergens during the critical postnatal period may lead to sensitization in early childhood. Consistent evidence indicates that children sensitized to common indoor allergens are at several-fold higher risk of asthma and allergy. Due to conflicting evidence from prospective studies, some doubt remains regarding a direct and dose-response relationship between exposure and development of asthma. However, in recent years, evidence has accumulated that exposure to indoor allergen causes asthma and allergy, but this effect may depend on dose and type of allergen as well as the underlying genetic susceptibility of the child.

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More information

Published date: 24 December 2009
Keywords: asthma, allergen, prevention, environment, allergy, atopy

Identifiers

Local EPrints ID: 194441
URI: http://eprints.soton.ac.uk/id/eprint/194441
ISSN: 1529-7322
PURE UUID: 2fb37788-e373-4e59-aded-40cd4a5ae6cc

Catalogue record

Date deposited: 28 Jul 2011 09:23
Last modified: 14 Mar 2024 03:59

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