The University of Southampton
University of Southampton Institutional Repository

Interferon alpha (pegylated and non-pegylated) and ribavirin for the treatment of mild chronic hepatitis C: a systematic review and economic evaluation

Shepherd, J., Jones, J., Hartwell, D., Davidson, P., Price, A. R. and Waugh, N. (2007) Interferon alpha (pegylated and non-pegylated) and ribavirin for the treatment of mild chronic hepatitis C: a systematic review and economic evaluation Health Technology Assessment, 11, (11), pp. 1-205. (doi:10.3310/hta11110). (PMID:17346498).

Record type: Article

Abstract

This systematic review and economic evaluation show that patients with histologically mild HCV can be successfully treated with both pegylated and non-pegylated interferon alpha. Early treatment and watchful waiting strategies are associated with acceptable cost-per-QALY estimates. Research needs to be directed towards newer, potentially more effective interventions, particularly those that improve treatment response in patients with genotype 1, with minimal adverse effects. Further research is required into the natural history of HCV to estimate better the rate of liver disease progression, and also into the effectiveness of non-invasive biochemical markers of liver disease, as an alternative to liver biopsy

Full text not available from this repository.

More information

Published date: March 2007
Organisations: Faculty of Medicine

Identifiers

Local EPrints ID: 194787
URI: http://eprints.soton.ac.uk/id/eprint/194787
ISSN: 1366-5278
PURE UUID: 3db8de3a-20b0-4a81-a8d1-dd4fd2d82edd
ORCID for P. Davidson: ORCID iD orcid.org/0000-0003-0388-6356

Catalogue record

Date deposited: 11 Aug 2011 13:56
Last modified: 18 Jul 2017 11:26

Export record

Altmetrics

Contributors

Author: J. Shepherd
Author: J. Jones
Author: D. Hartwell
Author: P. Davidson ORCID iD
Author: A. R. Price
Author: N. Waugh

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×