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Integrating natural product synthesis and combinatorial chemistry

Integrating natural product synthesis and combinatorial chemistry
Integrating natural product synthesis and combinatorial chemistry
The fields of natural product total synthesis and combinatorial chemistry have major differences as well as much in common. Unique to combinatorial chemistry is the need to devise rapid and efficient methods for parallel synthesis and purification, while an area of overlap is the targeting of natural product scaffolds for combinatorial libraries. Both these aspects are illustrated with examples from our research.
solid-phase synthesis, demethoxyfumitremorgin-c analogs, fumiquinazoline alkaloids, condensation, library
0033-4545
1033-1039
Ganesan, A.
62aa5a87-9308-4383-8686-99726b6bcfb9
Ganesan, A.
62aa5a87-9308-4383-8686-99726b6bcfb9

Ganesan, A. (2001) Integrating natural product synthesis and combinatorial chemistry. Pure and Applied Chemistry, 73 (7), 1033-1039.

Record type: Article

Abstract

The fields of natural product total synthesis and combinatorial chemistry have major differences as well as much in common. Unique to combinatorial chemistry is the need to devise rapid and efficient methods for parallel synthesis and purification, while an area of overlap is the targeting of natural product scaffolds for combinatorial libraries. Both these aspects are illustrated with examples from our research.

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More information

Published date: 1 July 2001
Keywords: solid-phase synthesis, demethoxyfumitremorgin-c analogs, fumiquinazoline alkaloids, condensation, library

Identifiers

Local EPrints ID: 19490
URI: http://eprints.soton.ac.uk/id/eprint/19490
ISSN: 0033-4545
PURE UUID: 37e282b0-62ea-40e7-a557-b7313030545d

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Date deposited: 15 Feb 2006
Last modified: 15 Jul 2019 19:27

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