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Linear fluorescent oligonucleotide probes with an acridine quencher generate a signal upon hybridisation

Linear fluorescent oligonucleotide probes with an acridine quencher generate a signal upon hybridisation
Linear fluorescent oligonucleotide probes with an acridine quencher generate a signal upon hybridisation
Linear, single stranded probes incorporating a fluorophore and an acridine moiety are weakly fluorescent until hybridised to a complementary target nucleic acid whereupon fluorescence increases due to reduced quenching.
molecular beacons, mutation
1359-7345
1480-1481
Ranasinghe, R.T.
e74a790d-e63a-40bc-9f5c-474fd63c75d8
Brown, L.J.
75aa95fa-5d27-46a7-9dbe-0f465a664f5b
Brown, T.
a64aae36-bb30-42df-88a2-11be394e8c89
Ranasinghe, R.T.
e74a790d-e63a-40bc-9f5c-474fd63c75d8
Brown, L.J.
75aa95fa-5d27-46a7-9dbe-0f465a664f5b
Brown, T.
a64aae36-bb30-42df-88a2-11be394e8c89

Ranasinghe, R.T., Brown, L.J. and Brown, T. (2001) Linear fluorescent oligonucleotide probes with an acridine quencher generate a signal upon hybridisation. Chemical Communications, (16), 1480-1481. (doi:10.1039/b104421b).

Record type: Article

Abstract

Linear, single stranded probes incorporating a fluorophore and an acridine moiety are weakly fluorescent until hybridised to a complementary target nucleic acid whereupon fluorescence increases due to reduced quenching.

Full text not available from this repository.

More information

Published date: 21 August 2001
Keywords: molecular beacons, mutation

Identifiers

Local EPrints ID: 19605
URI: http://eprints.soton.ac.uk/id/eprint/19605
ISSN: 1359-7345
PURE UUID: 3b8a6b26-3816-49b1-8e1c-a5839a37ba79
ORCID for L.J. Brown: ORCID iD orcid.org/0000-0002-5678-0814

Catalogue record

Date deposited: 14 Feb 2006
Last modified: 03 Dec 2019 01:56

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