Structure of bis(2-acetylpyridine 3-hexamethyleneiminylthiosemicarbazonato) palladium(II), a potential antitumor complex
Structure of bis(2-acetylpyridine 3-hexamethyleneiminylthiosemicarbazonato) palladium(II), a potential antitumor complex
The crystal structure of the potential antitumor complex bis(2-acetyppyridine 3-hexamethyleneiminylthiosemicarbazonato)palladium(II) has been solved. The palladium(H) atom is in a square planar environment surrounded by two cis nitrogen atoms and two cis sulfur atoms. The ligands are not equivalent, one being tridentate with (N,N,S) donation, the other being monodentate using only the sulfur atom to coordinate to the metal. The tridentate ligand shows a Z, E, Z configuration while the monodentate ligand shows an E, E, Z. Intermolecular hydrogen bonds stabilize the structure, while the crystal packing is determined by Pd-C, Pd-?, C-H-? and ?-? interactions.
palladium(ii) complexes, thiosemicarbazonato complexes, crystal
structure, antitumor activity, spectral properties, 2-acetylpyridine, thiosemicarbazone, derivatives
137-140
Kovala-Demertzi, Dimitra
f1f7122a-ea60-4b34-a882-a3ef4416282e
Demertzis, Mavroudis A.
2096f486-765f-4916-982d-b8676ee72b10
Miller, John R.
51ae0abf-cda3-459e-bc0d-e449e8371589
Frampton, Christopher S.
91f7b381-6040-4c82-94d7-4edf37c71549
Jasinski, Jerry P.
7d01281e-3b67-41ca-a875-f360189a9edb
West, Douglas X.
91ef63ae-0eb0-46fd-ab05-2a0ab9233d27
11 November 2002
Kovala-Demertzi, Dimitra
f1f7122a-ea60-4b34-a882-a3ef4416282e
Demertzis, Mavroudis A.
2096f486-765f-4916-982d-b8676ee72b10
Miller, John R.
51ae0abf-cda3-459e-bc0d-e449e8371589
Frampton, Christopher S.
91f7b381-6040-4c82-94d7-4edf37c71549
Jasinski, Jerry P.
7d01281e-3b67-41ca-a875-f360189a9edb
West, Douglas X.
91ef63ae-0eb0-46fd-ab05-2a0ab9233d27
Kovala-Demertzi, Dimitra, Demertzis, Mavroudis A., Miller, John R., Frampton, Christopher S., Jasinski, Jerry P. and West, Douglas X.
(2002)
Structure of bis(2-acetylpyridine 3-hexamethyleneiminylthiosemicarbazonato) palladium(II), a potential antitumor complex.
Journal of Inorganic Biochemistry, 92 (2), .
(doi:10.1016/S0162-0134(02)00493-2).
Abstract
The crystal structure of the potential antitumor complex bis(2-acetyppyridine 3-hexamethyleneiminylthiosemicarbazonato)palladium(II) has been solved. The palladium(H) atom is in a square planar environment surrounded by two cis nitrogen atoms and two cis sulfur atoms. The ligands are not equivalent, one being tridentate with (N,N,S) donation, the other being monodentate using only the sulfur atom to coordinate to the metal. The tridentate ligand shows a Z, E, Z configuration while the monodentate ligand shows an E, E, Z. Intermolecular hydrogen bonds stabilize the structure, while the crystal packing is determined by Pd-C, Pd-?, C-H-? and ?-? interactions.
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Published date: 11 November 2002
Keywords:
palladium(ii) complexes, thiosemicarbazonato complexes, crystal
structure, antitumor activity, spectral properties, 2-acetylpyridine, thiosemicarbazone, derivatives
Identifiers
Local EPrints ID: 19789
URI: http://eprints.soton.ac.uk/id/eprint/19789
ISSN: 0162-0134
PURE UUID: ff0fedac-fc4a-46ec-8569-74afcaf21bb9
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Date deposited: 21 Feb 2006
Last modified: 15 Mar 2024 06:19
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Contributors
Author:
Dimitra Kovala-Demertzi
Author:
Mavroudis A. Demertzis
Author:
John R. Miller
Author:
Christopher S. Frampton
Author:
Jerry P. Jasinski
Author:
Douglas X. West
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