The University of Southampton
University of Southampton Institutional Repository

Synthesis of functionalized 1,5-cyclooctadienes by LICKOR metalation

Synthesis of functionalized 1,5-cyclooctadienes by LICKOR metalation
Synthesis of functionalized 1,5-cyclooctadienes by LICKOR metalation
1,5-Cyclooctadiene was lithiated under LICKOR superbase conditions followed by reaction with alkyl halides or ethylene oxide to yield 3-substituted 1,5-cyclooetadienes in high yield and purity. This procedure is suitable for preparation of 1,5-cyclooctadienes carrying pendant functional groups for immobilization on solid-phase resins.
9-borabicyclononane 9-bbn, organic-synthesis, superbases, route
0022-3263
6250-6252
Revell, J. D.
cf4a46e3-2280-492e-9dab-020fdec8b47b
Ganesan, A.
62aa5a87-9308-4383-8686-99726b6bcfb9
Revell, J. D.
cf4a46e3-2280-492e-9dab-020fdec8b47b
Ganesan, A.
62aa5a87-9308-4383-8686-99726b6bcfb9

Revell, J. D. and Ganesan, A. (2002) Synthesis of functionalized 1,5-cyclooctadienes by LICKOR metalation. Journal of Organic Chemistry, 67 (17), 6250-6252. (doi:10.1021/jo025715u).

Record type: Article

Abstract

1,5-Cyclooctadiene was lithiated under LICKOR superbase conditions followed by reaction with alkyl halides or ethylene oxide to yield 3-substituted 1,5-cyclooetadienes in high yield and purity. This procedure is suitable for preparation of 1,5-cyclooctadienes carrying pendant functional groups for immobilization on solid-phase resins.

This record has no associated files available for download.

More information

Published date: 23 August 2002
Keywords: 9-borabicyclononane 9-bbn, organic-synthesis, superbases, route

Identifiers

Local EPrints ID: 19843
URI: http://eprints.soton.ac.uk/id/eprint/19843
ISSN: 0022-3263
PURE UUID: 9976a510-efef-495f-9196-2b5350969dc1

Catalogue record

Date deposited: 20 Feb 2006
Last modified: 08 Jan 2022 15:48

Export record

Altmetrics

Contributors

Author: J. D. Revell
Author: A. Ganesan

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×