Patient-reported outcomes in clinical trials of inhaled asthma medications: systematic review and research needs
Patient-reported outcomes in clinical trials of inhaled asthma medications: systematic review and research needs
Numerous validated PRO instruments are available but it is unclear why few are used in asthma clinical trials. Problems include poor reporting, and uncritical analysis and interpretation of PRO scores. Research needs include identifying and recommending a set of PROs for use in asthma clinical research and providing guidance for researchers on the application, analysis and interpretation of PRO measures in clinical trials.
asthma-related quality of life, health-related quality of life, patient outcome assessments, symptom
scores ? Inhaled corticosteroids ? Beta-2 agonists
343-357
Frampton, Geoff
26c6163c-3428-45b8-b8b9-92091ff6c69f
Shepherd, Jonathan
dfbca97a-9307-4eee-bdf7-e27bcb02bc67
April 2011
Frampton, Geoff
26c6163c-3428-45b8-b8b9-92091ff6c69f
Shepherd, Jonathan
dfbca97a-9307-4eee-bdf7-e27bcb02bc67
Frampton, Geoff and Shepherd, Jonathan
(2011)
Patient-reported outcomes in clinical trials of inhaled asthma medications: systematic review and research needs.
Quality of Life Research, 20 (3), .
(doi:10.1007/s11136-010-9750-1).
(PMID:20945162)
Abstract
Numerous validated PRO instruments are available but it is unclear why few are used in asthma clinical trials. Problems include poor reporting, and uncritical analysis and interpretation of PRO scores. Research needs include identifying and recommending a set of PROs for use in asthma clinical research and providing guidance for researchers on the application, analysis and interpretation of PRO measures in clinical trials.
Text
Frampton & Shepherd Qual Life Res post-referee accepted version.pdf
- Accepted Manuscript
Text
Frampton & Shepherd Appendix A.pdf
- Accepted Manuscript
Text
Frampton & Shepherd Supplementary Table S1 (overview of instruments).pdf
- Other
More information
Published date: April 2011
Keywords:
asthma-related quality of life, health-related quality of life, patient outcome assessments, symptom
scores ? Inhaled corticosteroids ? Beta-2 agonists
Organisations:
Faculty of Medicine
Identifiers
Local EPrints ID: 198517
URI: http://eprints.soton.ac.uk/id/eprint/198517
ISSN: 0962-9343
PURE UUID: 2b03a8a9-18dc-49db-be61-14083978df65
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Date deposited: 25 Oct 2011 11:50
Last modified: 15 Mar 2024 02:48
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