The University of Southampton
University of Southampton Institutional Repository

Patient-reported outcomes in clinical trials of inhaled asthma medications: systematic review and research needs

Patient-reported outcomes in clinical trials of inhaled asthma medications: systematic review and research needs
Patient-reported outcomes in clinical trials of inhaled asthma medications: systematic review and research needs
Numerous validated PRO instruments are available but it is unclear why few are used in asthma clinical trials. Problems include poor reporting, and uncritical analysis and interpretation of PRO scores. Research needs include identifying and recommending a set of PROs for use in asthma clinical research and providing guidance for researchers on the application, analysis and interpretation of PRO measures in clinical trials.
asthma-related quality of life, health-related quality of life, patient outcome assessments, symptom scores ? Inhaled corticosteroids ? Beta-2 agonists
0962-9343
343-357
Frampton, Geoff
26c6163c-3428-45b8-b8b9-92091ff6c69f
Shepherd, Jonathan
dfbca97a-9307-4eee-bdf7-e27bcb02bc67
Frampton, Geoff
26c6163c-3428-45b8-b8b9-92091ff6c69f
Shepherd, Jonathan
dfbca97a-9307-4eee-bdf7-e27bcb02bc67

Frampton, Geoff and Shepherd, Jonathan (2011) Patient-reported outcomes in clinical trials of inhaled asthma medications: systematic review and research needs. Quality of Life Research, 20 (3), 343-357. (doi:10.1007/s11136-010-9750-1). (PMID:20945162)

Record type: Article

Abstract

Numerous validated PRO instruments are available but it is unclear why few are used in asthma clinical trials. Problems include poor reporting, and uncritical analysis and interpretation of PRO scores. Research needs include identifying and recommending a set of PROs for use in asthma clinical research and providing guidance for researchers on the application, analysis and interpretation of PRO measures in clinical trials.

Text
Frampton & Shepherd Qual Life Res post-referee accepted version.pdf - Accepted Manuscript
Download (317kB)
Text
Frampton & Shepherd Appendix A.pdf - Accepted Manuscript
Download (378kB)
Text
Frampton & Shepherd Supplementary Table S1 (overview of instruments).pdf - Other
Download (152kB)

More information

Published date: April 2011
Keywords: asthma-related quality of life, health-related quality of life, patient outcome assessments, symptom scores ? Inhaled corticosteroids ? Beta-2 agonists
Organisations: Faculty of Medicine

Identifiers

Local EPrints ID: 198517
URI: http://eprints.soton.ac.uk/id/eprint/198517
ISSN: 0962-9343
PURE UUID: 2b03a8a9-18dc-49db-be61-14083978df65
ORCID for Geoff Frampton: ORCID iD orcid.org/0000-0003-2005-0497
ORCID for Jonathan Shepherd: ORCID iD orcid.org/0000-0003-1682-4330

Catalogue record

Date deposited: 25 Oct 2011 11:50
Last modified: 18 Feb 2021 16:44

Export record

Altmetrics

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×