Zhu, X. W. and Ganesan, A.
Regioselective synthesis of 3-alkylindoles mediated by zinc triflate
Journal of Organic Chemistry, 67, (8), . (doi:10.1021/jo010996b).
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Zinc triflate was found to be an effective reagent for the C3-alkylation of indoles by alkyl halides in the presence of Hunig's base and tetrabutylammonium iodide. This new method for indole alkylation proceeds by a S(N)1-like pathway, and is general for allylic, benzylic, and tertiary halides.
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