Dalrymple-Hay, M. J, Lucas, J.S., Connett, G. and Lea, R. E.
Lung resection for the treatment of severe localised bronchiectasis in cystic fibrosis patients
Acta Chirurgica Hungarica, 38, (1), . (PMID:10439089).
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BACKGROUND: A small proportion of cystic fibrosis patients develop severe localised bronchiectasis. When this persists despite maximal medical therapy it presents a difficult management problem. Lung transplantation cannot be justified. We report encouraging results in six patients with severe localised bronchiectasis and cystic fibrosis who underwent pulmonary resection.
METHODS: Each child had severe localised bronchiectasis despite maximal medical therapy. Intensive preoperative toilet was instituted and pulmonary resection undertaken when lung function was optimal.
RESULTS: There was a marked improvement in symptoms in every case. No significant long-standing morbidity was associated with the resection. There was no significant decrease in pulmonary function following resection.
CONCLUSION: Pulmonary resection should be considered in the management of severe localised bronchiectasis unresponsive to maximal medical therapy in cystic fibrosis patients.
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