Hybrid approach to high-frequency microfluidic mixing
Hybrid approach to high-frequency microfluidic mixing
We report the experimental verification of the predicted chaotic mixing characteristics for a polydimethylsioxane microfluidic chip, based on the mechanism of multistage cross-channel flows. While chaotic mixing can be achieved within short passage distances, there is an optimal side channel flow pulsation frequency beyond which the mixing becomes ineffective. Based on the physical understanding of a Poincaré section analysis, we propose the installation of passive flow baffles in the main microfluidic channel to facilitate high-frequency mixing. The combined hybrid approach enables chaotic mixing at enhanced frequency and reduced passage distance in two-dimensional flows.
44501
Niu, Xize
f3d964fb-23b4-45db-92fe-02426e4e76fa
Liu, Liyu
7c5add79-f11f-44f6-bead-1005620a151a
Wen, Weijia
8077209d-a633-4e3c-b0b6-16ddddb7a153
Sheng, Ping
4552ac2e-9e10-427f-a8b2-7d23c4a3a150
2006
Niu, Xize
f3d964fb-23b4-45db-92fe-02426e4e76fa
Liu, Liyu
7c5add79-f11f-44f6-bead-1005620a151a
Wen, Weijia
8077209d-a633-4e3c-b0b6-16ddddb7a153
Sheng, Ping
4552ac2e-9e10-427f-a8b2-7d23c4a3a150
Niu, Xize, Liu, Liyu, Wen, Weijia and Sheng, Ping
(2006)
Hybrid approach to high-frequency microfluidic mixing.
Physical Review Letters, 97 (4), .
(doi:10.1103/PhysRevLett.97.044501).
Abstract
We report the experimental verification of the predicted chaotic mixing characteristics for a polydimethylsioxane microfluidic chip, based on the mechanism of multistage cross-channel flows. While chaotic mixing can be achieved within short passage distances, there is an optimal side channel flow pulsation frequency beyond which the mixing becomes ineffective. Based on the physical understanding of a Poincaré section analysis, we propose the installation of passive flow baffles in the main microfluidic channel to facilitate high-frequency mixing. The combined hybrid approach enables chaotic mixing at enhanced frequency and reduced passage distance in two-dimensional flows.
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Published date: 2006
Organisations:
Mechatronics
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Local EPrints ID: 199909
URI: http://eprints.soton.ac.uk/id/eprint/199909
PURE UUID: af39b5f9-3e33-4f8a-ab3f-72ef89a65c5a
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Date deposited: 27 Oct 2011 08:59
Last modified: 14 Mar 2024 04:18
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Author:
Liyu Liu
Author:
Weijia Wen
Author:
Ping Sheng
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