Lingard, Iain, Bhalay, Gurdip and Bradley, Mark (2003) Hexadienyloxycarbonyl (Hdoc) - a mild acid labile protecting group for amines. Synlett, (12), 1791-1792. (doi:10.1055/s-2003-41501).
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Article
Abstract
Hexadienyloxycarbonyl is an amine protecting group which can be cleaved with 1% TFA in CH2Cl2. It is stable to Pd(0) and basic conditions and is proposed as a useful alternative to the trityl and Bpoc protecting groups.
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Published date: 29 September 2003
Keywords:
protecting groups, amines, amino acids, cleavage, protonations solid-phase synthesis, peptides
Identifiers
Local EPrints ID: 20026
URI: http://eprints.soton.ac.uk/id/eprint/20026
ISSN: 0936-5214
PURE UUID: 70b4fd88-ab45-48b5-aa47-889b88b34ba3
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Date deposited: 24 Feb 2006
Last modified: 15 Mar 2024 06:21
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Contributors
Author:
Iain Lingard
Author:
Gurdip Bhalay
Author:
Mark Bradley
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