The University of Southampton
University of Southampton Institutional Repository

Isolation and structure determination of an antimicrobial ester from a marine sediment-derived bacterium

Isolation and structure determination of an antimicrobial ester from a marine sediment-derived bacterium
Isolation and structure determination of an antimicrobial ester from a marine sediment-derived bacterium
A new compound, assigned the trivial name bonactin (1), has been isolated from the liquid culture of a Streptomyces sp. BD21-2 obtained from a shallow-water sediment sample collected at Kailua Beach, Oahu, Hawaii. Structure elucidation employed one- and two-dimensional NMR, HRFABMS, IR, and chemical analysis. Bonactin displayed antimicrobial activity against both Gram-positive and Gram-negative bacteria as well as antifungal activity.
nonactin, metabolites, acid
0163-3864
1291-1293
Schumacher, Robert W.
e6b8d82a-00a9-477c-a085-5798e84fe209
Talmage, Stephanie C.
c1eb786b-c6c8-4b69-ad13-c3155730a107
Miller, Sara A.
9e7a1640-bbf0-4be5-b5bd-2f240444efb8
Sarris, Katie E.
a53d4a4f-56ad-4542-9423-306d2a159028
Davidson, Bradley S.
708f2855-d8b9-467f-8401-401e2426746c
Goldberg, Arthur
351eca51-6b10-4ddc-9f97-f534be3e8774
Schumacher, Robert W.
e6b8d82a-00a9-477c-a085-5798e84fe209
Talmage, Stephanie C.
c1eb786b-c6c8-4b69-ad13-c3155730a107
Miller, Sara A.
9e7a1640-bbf0-4be5-b5bd-2f240444efb8
Sarris, Katie E.
a53d4a4f-56ad-4542-9423-306d2a159028
Davidson, Bradley S.
708f2855-d8b9-467f-8401-401e2426746c
Goldberg, Arthur
351eca51-6b10-4ddc-9f97-f534be3e8774

Schumacher, Robert W., Talmage, Stephanie C., Miller, Sara A., Sarris, Katie E., Davidson, Bradley S. and Goldberg, Arthur (2003) Isolation and structure determination of an antimicrobial ester from a marine sediment-derived bacterium. Journal of Natural Products, 66 (9), 1291-1293. (doi:10.1021/np020594e).

Record type: Article

Abstract

A new compound, assigned the trivial name bonactin (1), has been isolated from the liquid culture of a Streptomyces sp. BD21-2 obtained from a shallow-water sediment sample collected at Kailua Beach, Oahu, Hawaii. Structure elucidation employed one- and two-dimensional NMR, HRFABMS, IR, and chemical analysis. Bonactin displayed antimicrobial activity against both Gram-positive and Gram-negative bacteria as well as antifungal activity.

This record has no associated files available for download.

More information

Published date: 1 September 2003
Keywords: nonactin, metabolites, acid

Identifiers

Local EPrints ID: 20077
URI: http://eprints.soton.ac.uk/id/eprint/20077
ISSN: 0163-3864
PURE UUID: c092e53c-580a-4bc6-851b-c57c9b67747b

Catalogue record

Date deposited: 24 Feb 2006
Last modified: 15 Mar 2024 06:21

Export record

Altmetrics

Contributors

Author: Robert W. Schumacher
Author: Stephanie C. Talmage
Author: Sara A. Miller
Author: Katie E. Sarris
Author: Bradley S. Davidson
Author: Arthur Goldberg

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×