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Highly efficient Lewis acid-catalysed Pictet-Spengler reactions discovered by parallel screening

Highly efficient Lewis acid-catalysed Pictet-Spengler reactions discovered by parallel screening
Highly efficient Lewis acid-catalysed Pictet-Spengler reactions discovered by parallel screening
High yielding Lewis acid-catalysed one-pot Pictet-Spengler reactions of tryptophan methyl ester and tryptamine with aliphatic and aromatic aldehydes were achieved in short reaction times with the aid of microwave irradiation.
microwave-assisted reactions, temperature ionic liquids, chiral auxiliary groups, n-b-hydroxytryptamine, demethoxyfumitremorgin-c, organic-synthesis, solid-phase, amino-acids, aldehydes, 1, 2, 3, 4-tetrahydro-beta-carbolines
1359-7345
916-917
Srinivasan, N.
ec85721a-8212-4f44-a230-b16e4b0664c2
Ganesan, A.
62aa5a87-9308-4383-8686-99726b6bcfb9
Srinivasan, N.
ec85721a-8212-4f44-a230-b16e4b0664c2
Ganesan, A.
62aa5a87-9308-4383-8686-99726b6bcfb9

Srinivasan, N. and Ganesan, A. (2003) Highly efficient Lewis acid-catalysed Pictet-Spengler reactions discovered by parallel screening. Chemical Communications, 2003 (7), 916-917. (doi:10.1039/b212063a).

Record type: Article

Abstract

High yielding Lewis acid-catalysed one-pot Pictet-Spengler reactions of tryptophan methyl ester and tryptamine with aliphatic and aromatic aldehydes were achieved in short reaction times with the aid of microwave irradiation.

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More information

Published date: 2003
Keywords: microwave-assisted reactions, temperature ionic liquids, chiral auxiliary groups, n-b-hydroxytryptamine, demethoxyfumitremorgin-c, organic-synthesis, solid-phase, amino-acids, aldehydes, 1, 2, 3, 4-tetrahydro-beta-carbolines

Identifiers

Local EPrints ID: 20084
URI: http://eprints.soton.ac.uk/id/eprint/20084
ISSN: 1359-7345
PURE UUID: 360e68dd-9991-483d-a98a-80026bf22019

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Date deposited: 22 Feb 2006
Last modified: 15 Mar 2024 06:21

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Contributors

Author: N. Srinivasan
Author: A. Ganesan

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