The University of Southampton
University of Southampton Institutional Repository

Modular three-component solid-phase synthesis of unsymmetrical guanidines via resin capture of carbodiimides

Modular three-component solid-phase synthesis of unsymmetrical guanidines via resin capture of carbodiimides
Modular three-component solid-phase synthesis of unsymmetrical guanidines via resin capture of carbodiimides
Because of their basicity and hydrogen-bonding properties, guanidines are an important functional group in many biologically active compounds of natural or synthetic origin. Consequently, methodologies for the parallel synthesis of guanidines have attracted much attention from both academia and industry. Numerous solid-phase routes have been reported, and the vast majority of these involve either urea or thiourea precursors or guanidine synthesis from pseudoureas or similarly activated amidines.
substituted guanidines, n, n', n'-substituted guanidines, staudinger reaction, annulation reaction, cyclic guanidines, organic-synthesis, linker, strategy, derivatives, reagents
1520-4766
32-34
Boguszewski, Paul A.
a3204dc6-3471-456b-86d7-6fa08d043eb8
Rahman, Shahzad S.
1b62eb43-fac6-4fec-b8f8-b5c167b7b820
Ganesan, A.
62aa5a87-9308-4383-8686-99726b6bcfb9
Boguszewski, Paul A.
a3204dc6-3471-456b-86d7-6fa08d043eb8
Rahman, Shahzad S.
1b62eb43-fac6-4fec-b8f8-b5c167b7b820
Ganesan, A.
62aa5a87-9308-4383-8686-99726b6bcfb9

Boguszewski, Paul A., Rahman, Shahzad S. and Ganesan, A. (2004) Modular three-component solid-phase synthesis of unsymmetrical guanidines via resin capture of carbodiimides. Journal of Combinatorial Chemistry, 6 (1), 32-34. (doi:10.1021/cc034036+).

Record type: Article

Abstract

Because of their basicity and hydrogen-bonding properties, guanidines are an important functional group in many biologically active compounds of natural or synthetic origin. Consequently, methodologies for the parallel synthesis of guanidines have attracted much attention from both academia and industry. Numerous solid-phase routes have been reported, and the vast majority of these involve either urea or thiourea precursors or guanidine synthesis from pseudoureas or similarly activated amidines.

Full text not available from this repository.

More information

Published date: 2004
Keywords: substituted guanidines, n, n', n'-substituted guanidines, staudinger reaction, annulation reaction, cyclic guanidines, organic-synthesis, linker, strategy, derivatives, reagents

Identifiers

Local EPrints ID: 20139
URI: https://eprints.soton.ac.uk/id/eprint/20139
ISSN: 1520-4766
PURE UUID: ec646351-22e0-498e-9574-5a5421e28729

Catalogue record

Date deposited: 23 Feb 2006
Last modified: 15 Jul 2019 19:26

Export record

Altmetrics

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of https://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×