An analogue of adenine that forms an 'A : T' base pair of comparable stability to G : C


Booth, J., Cummins, W. J. and Brown, T. (2004) An analogue of adenine that forms an 'A : T' base pair of comparable stability to G : C Chemical Communications, (19), pp. 2208-2209. (doi:10.1039/b409155h).

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Description/Abstract

The heterocyclic base 7-aminopropargyl-7-deaza-2,6-diaminopurine (D) has been incorporated into oligodeoxynucleotides. D: T has similar thermodynamic stability to G:C and is a stable analogue of A:T.

Item Type: Article
Digital Object Identifier (DOI): doi:10.1039/b409155h
ISSNs: 1359-7345 (print)
Related URLs:
Keywords: dna, oligonucleotides, duplex, pyrimidines
Subjects:
ePrint ID: 20142
Date :
Date Event
2004Published
Date Deposited: 22 Feb 2006
Last Modified: 16 Apr 2017 22:59
Further Information:Google Scholar
URI: http://eprints.soton.ac.uk/id/eprint/20142

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