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An analogue of adenine that forms an 'A : T' base pair of comparable stability to G : C

Booth, J., Cummins, W. J. and Brown, T. (2004) An analogue of adenine that forms an 'A : T' base pair of comparable stability to G : C Chemical Communications, (19), pp. 2208-2209. (doi:10.1039/b409155h).

Record type: Article

Abstract

The heterocyclic base 7-aminopropargyl-7-deaza-2,6-diaminopurine (D) has been incorporated into oligodeoxynucleotides. D: T has similar thermodynamic stability to G:C and is a stable analogue of A:T.

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Published date: 2004
Keywords: dna, oligonucleotides, duplex, pyrimidines

Identifiers

Local EPrints ID: 20142
URI: http://eprints.soton.ac.uk/id/eprint/20142
ISSN: 1359-7345
PURE UUID: aa2c983e-c4eb-4bb6-a3ac-2bac6f81ba4f

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Date deposited: 22 Feb 2006
Last modified: 17 Jul 2017 16:29

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Contributors

Author: J. Booth
Author: W. J. Cummins
Author: T. Brown

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