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Full orthogonality between Dde and Fmoc: the direct synthesis of PNA-peptide conjugates

Full orthogonality between Dde and Fmoc: the direct synthesis of PNA-peptide conjugates
Full orthogonality between Dde and Fmoc: the direct synthesis of PNA-peptide conjugates
New deprotection conditions for the Dde amine protecting group that are fully orthogonal to Fmoc are described and successfully applied to the dual synthesis of PNA-peptide conjugates.
nuclear-localization signal, acid, dna, hydroxylamine, mechanism, oligomers, polyamide, efficient
1523-7060
1127-1129
Diaz-Mochón, Juan Jose
4155e92a-6da9-4aa4-97d0-88c48a1f48e0
Bialy, Laurant
cbd32bc2-f89d-4008-a0df-24d056903c41
Bradley, Mark
562b9add-34c4-4620-bfa1-c7c83a0f0900
Diaz-Mochón, Juan Jose
4155e92a-6da9-4aa4-97d0-88c48a1f48e0
Bialy, Laurant
cbd32bc2-f89d-4008-a0df-24d056903c41
Bradley, Mark
562b9add-34c4-4620-bfa1-c7c83a0f0900

Diaz-Mochón, Juan Jose, Bialy, Laurant and Bradley, Mark (2004) Full orthogonality between Dde and Fmoc: the direct synthesis of PNA-peptide conjugates. Organic Letters, 6 (7), 1127-1129. (doi:10.1021/ol049905y).

Record type: Article

Abstract

New deprotection conditions for the Dde amine protecting group that are fully orthogonal to Fmoc are described and successfully applied to the dual synthesis of PNA-peptide conjugates.

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More information

Published date: 1 April 2004
Keywords: nuclear-localization signal, acid, dna, hydroxylamine, mechanism, oligomers, polyamide, efficient

Identifiers

Local EPrints ID: 20182
URI: http://eprints.soton.ac.uk/id/eprint/20182
ISSN: 1523-7060
PURE UUID: befaf5c4-aa7c-45be-9ca8-ea1867a41cb4

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Date deposited: 22 Feb 2006
Last modified: 14 Sep 2021 20:25

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Contributors

Author: Juan Jose Diaz-Mochón
Author: Laurant Bialy
Author: Mark Bradley

University divisions

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