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(Bu3Sn)(2)-TBAF: a new combination reagent for the reduction and deuteration of aryl bromides and iodides

(Bu3Sn)(2)-TBAF: a new combination reagent for the reduction and deuteration of aryl bromides and iodides
(Bu3Sn)(2)-TBAF: a new combination reagent for the reduction and deuteration of aryl bromides and iodides
The combination of (Bu3Sn)(2) and TBAF has been shown to reduce aromatic bromides and iodides in excellent yields under mild conditions. When the residual water in TBAF is exchanged for D2O, the halogen is replaced by a deuterium atom.
facile
1359-7345
1966-1967
Harrowven, David C.
bddcfab6-dbde-49df-aec2-42abbcf5d10b
Guy, Ian L.
b7d1bed5-2418-43d4-bb05-1db8d1bcc2db
Nunn, Michael I.T.
6342f503-1178-4b99-9a89-4e42618a6a56
Harrowven, David C.
bddcfab6-dbde-49df-aec2-42abbcf5d10b
Guy, Ian L.
b7d1bed5-2418-43d4-bb05-1db8d1bcc2db
Nunn, Michael I.T.
6342f503-1178-4b99-9a89-4e42618a6a56

Harrowven, David C., Guy, Ian L. and Nunn, Michael I.T. (2004) (Bu3Sn)(2)-TBAF: a new combination reagent for the reduction and deuteration of aryl bromides and iodides. Chemical Communications, (17), 1966-1967. (doi:10.1039/b406103a).

Record type: Article

Abstract

The combination of (Bu3Sn)(2) and TBAF has been shown to reduce aromatic bromides and iodides in excellent yields under mild conditions. When the residual water in TBAF is exchanged for D2O, the halogen is replaced by a deuterium atom.

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More information

Published date: 2004
Additional Information: ChemComm
Keywords: facile

Identifiers

Local EPrints ID: 20219
URI: http://eprints.soton.ac.uk/id/eprint/20219
ISSN: 1359-7345
PURE UUID: 9577681c-78cf-48d8-9843-01cdadd81466
ORCID for David C. Harrowven: ORCID iD orcid.org/0000-0001-6730-3573

Catalogue record

Date deposited: 21 Feb 2006
Last modified: 16 Mar 2024 02:46

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Contributors

Author: Ian L. Guy
Author: Michael I.T. Nunn

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