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Combinatorial approaches to synthetic receptors. Review article

Combinatorial approaches to synthetic receptors. Review article
Combinatorial approaches to synthetic receptors. Review article
Combinatorial chemistry can be efficiently used for the synthesis and evaluation of binding properties of libraries of synthetic receptors. This approach has been applied particularly to ‘tweezer’ and other ‘multi-armed’ receptors, and has been used for the identification of receptors for peptides in aqueous media, and for the development of new sensors and sensor arrays.
artificial receptors, peptide receptors, selective binding, libraries, chemistry, scaffold, acid, identification, construction, molecules
1367-5931
305-310
Srinivasan, Natarajan
d853c4c5-da37-4a46-b102-9bb285812d32
Kilburn, Jeremy D.
e64ded70-825a-40ec-816b-c4605e007e7a
Srinivasan, Natarajan
d853c4c5-da37-4a46-b102-9bb285812d32
Kilburn, Jeremy D.
e64ded70-825a-40ec-816b-c4605e007e7a

Srinivasan, Natarajan and Kilburn, Jeremy D. (2004) Combinatorial approaches to synthetic receptors. Review article. Current Opinion in Chemical Biology, 8 (3), 305-310. (doi:10.1016/j.cbpa.2004.04.014).

Record type: Article

Abstract

Combinatorial chemistry can be efficiently used for the synthesis and evaluation of binding properties of libraries of synthetic receptors. This approach has been applied particularly to ‘tweezer’ and other ‘multi-armed’ receptors, and has been used for the identification of receptors for peptides in aqueous media, and for the development of new sensors and sensor arrays.

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More information

Published date: 1 June 2004
Keywords: artificial receptors, peptide receptors, selective binding, libraries, chemistry, scaffold, acid, identification, construction, molecules

Identifiers

Local EPrints ID: 20323
URI: http://eprints.soton.ac.uk/id/eprint/20323
ISSN: 1367-5931
PURE UUID: e053d3df-2f07-4c98-a1ca-b8b320493b9d

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Date deposited: 16 Feb 2006
Last modified: 15 Mar 2024 06:24

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Contributors

Author: Natarajan Srinivasan
Author: Jeremy D. Kilburn

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