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Growth in infancy and childhood and hospitalization for personality disorders in adulthood: the Helsinki birth cohort study

Growth in infancy and childhood and hospitalization for personality disorders in adulthood: the Helsinki birth cohort study
Growth in infancy and childhood and hospitalization for personality disorders in adulthood: the Helsinki birth cohort study
This study examined the associations between infant and childhood growth and severe personality disorders. Among 4,689 men and 4,200 women of the Helsinki Birth Cohort Study 1934–1944, 81 men and 68 women had been hospitalized with an ICD (?8, ?9, ?10) diagnosis of personality disorder in adulthood. Among men, slower gain in BMI between birth and 6 months, faster gain in weight and BMI between 6 months and 1 year, and slower gains in them between 7 and 11 years of age predicted an increased risk of hospitalization for personality disorders. Thinness at 6 months and again at 11 years also showed significant association with personality disorders among men. Among women, slower gain in height between 2 and 7 years predicted hospitalization for personality disorders. Our findings show the importance of early growth as a vulnerability factor of personality disorders severe enough to justify hospitalization.

0885-579X
620-633
Lahti, Marius
fd381704-d07d-4e9a-b592-adf2313d8bd6
Raikkonen, Katri
7f44cbef-84f3-4d77-9ccc-f026ce537dd8
Wahlbeck, Kristian
b88af34b-f33b-4b72-94f9-6fc06d0ed0c1
Heinonen, Kati
46bb57d0-1c33-4cdd-badf-d38a5fc61200
Forsén, Tom
71e12224-d830-4202-9b7c-ee8fe47a4d54
Kajantie, Eero
d68d55b6-6df1-4195-a914-44c738a6db93
Pesonen, Anu-Katriina
8cc53fef-f713-425e-bd01-8f1c53842351
Osmond, Clive
2677bf85-494f-4a78-adf8-580e1b8acb81
Barker, David J.P.
5c773838-b094-4ac1-999b-b5869717f243
Eriksson, Johan G.
e95e6451-67bb-4338-803e-7af310a920ac
Lahti, Marius
fd381704-d07d-4e9a-b592-adf2313d8bd6
Raikkonen, Katri
7f44cbef-84f3-4d77-9ccc-f026ce537dd8
Wahlbeck, Kristian
b88af34b-f33b-4b72-94f9-6fc06d0ed0c1
Heinonen, Kati
46bb57d0-1c33-4cdd-badf-d38a5fc61200
Forsén, Tom
71e12224-d830-4202-9b7c-ee8fe47a4d54
Kajantie, Eero
d68d55b6-6df1-4195-a914-44c738a6db93
Pesonen, Anu-Katriina
8cc53fef-f713-425e-bd01-8f1c53842351
Osmond, Clive
2677bf85-494f-4a78-adf8-580e1b8acb81
Barker, David J.P.
5c773838-b094-4ac1-999b-b5869717f243
Eriksson, Johan G.
e95e6451-67bb-4338-803e-7af310a920ac

Lahti, Marius, Raikkonen, Katri, Wahlbeck, Kristian, Heinonen, Kati, Forsén, Tom, Kajantie, Eero, Pesonen, Anu-Katriina, Osmond, Clive, Barker, David J.P. and Eriksson, Johan G. (2011) Growth in infancy and childhood and hospitalization for personality disorders in adulthood: the Helsinki birth cohort study. Journal of Personality Disorders, 25 (5), 620-633. (doi:10.1521/pedi.2011.25.5.620). (PMID:22023299)

Record type: Article

Abstract

This study examined the associations between infant and childhood growth and severe personality disorders. Among 4,689 men and 4,200 women of the Helsinki Birth Cohort Study 1934–1944, 81 men and 68 women had been hospitalized with an ICD (?8, ?9, ?10) diagnosis of personality disorder in adulthood. Among men, slower gain in BMI between birth and 6 months, faster gain in weight and BMI between 6 months and 1 year, and slower gains in them between 7 and 11 years of age predicted an increased risk of hospitalization for personality disorders. Thinness at 6 months and again at 11 years also showed significant association with personality disorders among men. Among women, slower gain in height between 2 and 7 years predicted hospitalization for personality disorders. Our findings show the importance of early growth as a vulnerability factor of personality disorders severe enough to justify hospitalization.

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Published date: October 2011
Organisations: Faculty of Medicine

Identifiers

Local EPrints ID: 205001
URI: http://eprints.soton.ac.uk/id/eprint/205001
ISSN: 0885-579X
PURE UUID: 160450e4-4ff9-4e12-973a-5dfacb226981
ORCID for Clive Osmond: ORCID iD orcid.org/0000-0002-9054-4655

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Date deposited: 01 Dec 2011 15:57
Last modified: 18 Feb 2021 16:45

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Contributors

Author: Marius Lahti
Author: Katri Raikkonen
Author: Kristian Wahlbeck
Author: Kati Heinonen
Author: Tom Forsén
Author: Eero Kajantie
Author: Anu-Katriina Pesonen
Author: Clive Osmond ORCID iD
Author: David J.P. Barker
Author: Johan G. Eriksson

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