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Implant-bone interface healing and adaptation in resurfacing hip replacement

Dickinson, A.S., Taylor, A.C. and Browne, M. (2012) Implant-bone interface healing and adaptation in resurfacing hip replacement Computer Methods in Biomechanics and Biomedical Engineering, 15, (9), pp. 935-947. (doi:10.1080/10255842.2011.567269).

Record type: Article


Hip resurfacing demonstrates good survivorship as a treatment for young patients with osteoarthritis, but occasional implant loosening failures occur. On the femoral side there is radiographic evidence suggesting that the implant stem bears load, which is thought to lead to proximal stress shielding and adaptive bone remodelling. Previous attempts aimed at reproducing clinically observed bone adaptations in response to the implant have not recreated the full set of common radiographic changes, so a modified bone adaptation algorithm was developed in an attempt to replicate more closely the effects of the prosthesis on the host bone. The algorithm features combined implant–bone interface healing and continuum bone remodelling. It was observed that remodelling simulations that accounted for progressive gap filling at the implant–bone interface predicted the closest periprosthetic bone density changes to clinical X-rays and DEXA data. This model may contribute to improved understanding of clinical failure mechanisms with traditional hip resurfacing designs and enable more detailed pre-clinical analysis of new designs.

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Submitted date: November 2010
e-pub ahead of print date: 5 May 2011
Published date: September 2012
Organisations: Bioengineering Group


Local EPrints ID: 206783
ISSN: 1025-5842
PURE UUID: e04d94fa-0eff-490f-a708-f65adfe6ec46
ORCID for A.S. Dickinson: ORCID iD
ORCID for M. Browne: ORCID iD

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Date deposited: 11 Jan 2012 11:39
Last modified: 18 Jul 2017 10:51

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Author: A.S. Dickinson ORCID iD
Author: A.C. Taylor
Author: M. Browne ORCID iD

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