Improved synthesis of enantiopure pseudo-C-2-symmetric 1,4-bis-epoxide building blocks from arabitol
Improved synthesis of enantiopure pseudo-C-2-symmetric 1,4-bis-epoxide building blocks from arabitol
An improved large-scale synthesis of 1,2:4,5-dianhydro-3-benzylarabitol and 1,2:4,5-dianhydroarabitol from arabitol is described.
2-directional chain synthesis, hiv-1 protease inhibitors, a-ring
precursors, d-mannitol, derivatives, analogs, configuration, enantiomers, epoxidation, metathesis
2449-2453
Leung, Leo M. H.
09d74d73-2251-4462-b171-27098a810519
Gibson, Vicky
c2078543-eead-4d7e-9e4b-be193c78f09e
Linclau, Bruno
172ac6fb-139d-4c3c-8bac-902420150d6a
18 July 2005
Leung, Leo M. H.
09d74d73-2251-4462-b171-27098a810519
Gibson, Vicky
c2078543-eead-4d7e-9e4b-be193c78f09e
Linclau, Bruno
172ac6fb-139d-4c3c-8bac-902420150d6a
Leung, Leo M. H., Gibson, Vicky and Linclau, Bruno
(2005)
Improved synthesis of enantiopure pseudo-C-2-symmetric 1,4-bis-epoxide building blocks from arabitol.
Tetrahedron: Asymmetry, 16 (14), .
(doi:10.1016/j.tetasy.2005.05.043).
Abstract
An improved large-scale synthesis of 1,2:4,5-dianhydro-3-benzylarabitol and 1,2:4,5-dianhydroarabitol from arabitol is described.
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Published date: 18 July 2005
Keywords:
2-directional chain synthesis, hiv-1 protease inhibitors, a-ring
precursors, d-mannitol, derivatives, analogs, configuration, enantiomers, epoxidation, metathesis
Identifiers
Local EPrints ID: 20849
URI: http://eprints.soton.ac.uk/id/eprint/20849
PURE UUID: 21f35ae4-510c-41cc-80e2-b314a8fbe060
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Date deposited: 01 Mar 2006
Last modified: 15 Mar 2024 06:26
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Contributors
Author:
Leo M. H. Leung
Author:
Vicky Gibson
Author:
Bruno Linclau
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