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Improved synthesis of enantiopure pseudo-C-2-symmetric 1,4-bis-epoxide building blocks from arabitol

Improved synthesis of enantiopure pseudo-C-2-symmetric 1,4-bis-epoxide building blocks from arabitol
Improved synthesis of enantiopure pseudo-C-2-symmetric 1,4-bis-epoxide building blocks from arabitol
An improved large-scale synthesis of 1,2:4,5-dianhydro-3-benzylarabitol and 1,2:4,5-dianhydroarabitol from arabitol is described.
2-directional chain synthesis, hiv-1 protease inhibitors, a-ring precursors, d-mannitol, derivatives, analogs, configuration, enantiomers, epoxidation, metathesis
2449-2453
Leung, Leo M. H.
09d74d73-2251-4462-b171-27098a810519
Gibson, Vicky
c2078543-eead-4d7e-9e4b-be193c78f09e
Linclau, Bruno
172ac6fb-139d-4c3c-8bac-902420150d6a
Leung, Leo M. H.
09d74d73-2251-4462-b171-27098a810519
Gibson, Vicky
c2078543-eead-4d7e-9e4b-be193c78f09e
Linclau, Bruno
172ac6fb-139d-4c3c-8bac-902420150d6a

Leung, Leo M. H., Gibson, Vicky and Linclau, Bruno (2005) Improved synthesis of enantiopure pseudo-C-2-symmetric 1,4-bis-epoxide building blocks from arabitol. Tetrahedron: Asymmetry, 16 (14), 2449-2453. (doi:10.1016/j.tetasy.2005.05.043).

Record type: Article

Abstract

An improved large-scale synthesis of 1,2:4,5-dianhydro-3-benzylarabitol and 1,2:4,5-dianhydroarabitol from arabitol is described.

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More information

Published date: 18 July 2005
Keywords: 2-directional chain synthesis, hiv-1 protease inhibitors, a-ring precursors, d-mannitol, derivatives, analogs, configuration, enantiomers, epoxidation, metathesis

Identifiers

Local EPrints ID: 20849
URI: http://eprints.soton.ac.uk/id/eprint/20849
PURE UUID: 21f35ae4-510c-41cc-80e2-b314a8fbe060

Catalogue record

Date deposited: 01 Mar 2006
Last modified: 15 Jul 2019 19:25

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