Sexual functioning in male survivors of lymphoma: a systematic review
Sexual functioning in male survivors of lymphoma: a systematic review
Introduction: the lymphomas [Hodgkin’s Lymphoma (HL) and Non-Hodgkin’s Lymphoma (NHL)] are among the most common cancers affecting men under 45 years. Survival rates are now excellent, but treatment is associated with a number of side effects including sexual dysfunction with potential implications for compromised QoL (quality of life).
Aims: to address the: (i) prevalence of sexual dysfunction among lymphoma survivors relative to the general population, survivors of other cancers, and in survivors of HL and NHL; and (ii) relationships between sexual functioning and disease and treatment, demographic, and psychological variables.
Methods: inclusion criteria were quantitative studies that focused on adult male survivors of lymphoma, included a comparison group and presented results separately for HL and NHL. Standardized systematic searches were used. Information about design, sample size, age, time since diagnosis, type of treatment, comparison group, measures and findings were extracted from eligible studies.
Results: ten articles met the inclusion criteria, of which nine included patients with HL only, and one included patients with HL or NHL. Sexual function was compromised relative to the general population, better than testicular cancer survivors, and worse than leukaemia survivors. Depression was consistently associated with sexual dysfunction. There was evidence that chemotherapy, relapse, reduced testosterone levels, older age at survey and worse physical QoL were associated with worse sexual function.
Conclusions: conclusions are limited by methodological issues including lack of utilization of standardized measures of sexual function and longitudinal research. Even so, there is evidence of sexual dysfunction among lymphoma survivors. Clinicians need to be sensitive to these issues. Future longitudinal work is necessary to determine the likelihood of recovery.
1833-1841
Arden-Close, Emily
476eebfb-e256-474b-8351-09db1efdeab5
Eiser, Christine
ee840c03-619d-4559-a971-e7a001fe360b
Pacey, Allan
417e31bd-db05-459e-9342-1fa0547cdf18
July 2011
Arden-Close, Emily
476eebfb-e256-474b-8351-09db1efdeab5
Eiser, Christine
ee840c03-619d-4559-a971-e7a001fe360b
Pacey, Allan
417e31bd-db05-459e-9342-1fa0547cdf18
Arden-Close, Emily, Eiser, Christine and Pacey, Allan
(2011)
Sexual functioning in male survivors of lymphoma: a systematic review.
The Journal of Sexual Medicine, 8 (7), .
(doi:10.1111/j.1743-6109.2011.02209.x.).
Abstract
Introduction: the lymphomas [Hodgkin’s Lymphoma (HL) and Non-Hodgkin’s Lymphoma (NHL)] are among the most common cancers affecting men under 45 years. Survival rates are now excellent, but treatment is associated with a number of side effects including sexual dysfunction with potential implications for compromised QoL (quality of life).
Aims: to address the: (i) prevalence of sexual dysfunction among lymphoma survivors relative to the general population, survivors of other cancers, and in survivors of HL and NHL; and (ii) relationships between sexual functioning and disease and treatment, demographic, and psychological variables.
Methods: inclusion criteria were quantitative studies that focused on adult male survivors of lymphoma, included a comparison group and presented results separately for HL and NHL. Standardized systematic searches were used. Information about design, sample size, age, time since diagnosis, type of treatment, comparison group, measures and findings were extracted from eligible studies.
Results: ten articles met the inclusion criteria, of which nine included patients with HL only, and one included patients with HL or NHL. Sexual function was compromised relative to the general population, better than testicular cancer survivors, and worse than leukaemia survivors. Depression was consistently associated with sexual dysfunction. There was evidence that chemotherapy, relapse, reduced testosterone levels, older age at survey and worse physical QoL were associated with worse sexual function.
Conclusions: conclusions are limited by methodological issues including lack of utilization of standardized measures of sexual function and longitudinal research. Even so, there is evidence of sexual dysfunction among lymphoma survivors. Clinicians need to be sensitive to these issues. Future longitudinal work is necessary to determine the likelihood of recovery.
Text
sexualfunction_eprint.docx
- Author's Original
Restricted to Repository staff only
More information
e-pub ahead of print date: 16 February 2011
Published date: July 2011
Identifiers
Local EPrints ID: 210297
URI: http://eprints.soton.ac.uk/id/eprint/210297
ISSN: 1743-6095
PURE UUID: 0e632d6b-9e48-44ae-b630-01519d033abf
Catalogue record
Date deposited: 08 Feb 2012 11:08
Last modified: 14 Mar 2024 04:48
Export record
Altmetrics
Contributors
Author:
Emily Arden-Close
Author:
Christine Eiser
Author:
Allan Pacey
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics