Tunable transmembrane chloride transport by bis-indolylureas

Haynes, Cally J.E., Moore, Stephen J., Hiscock, Jennifer R., Marques, Igor, Costa, Paulo Jorge, Félix, Vítor and Gale, Philip A. (2012) Tunable transmembrane chloride transport by bis-indolylureas Chemical Science, 3, pp. 1436-1444. (doi:10.1039/C2SC20041D).


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A series of bis-indolylureas have been found to mediate chloride transport across vesicle bilayers. The anion transport activity of these receptors may be readily modulated by small structural changes to the receptor scaffold as shown by the combination of experimental chloride efflux studies and molecular dynamics simulations in water and POPC bilayer

Item Type: Article
Digital Object Identifier (DOI): doi:10.1039/C2SC20041D
ISSNs: 1478-6524 (print)
ePrint ID: 210962
Date :
Date Event
9 February 2012e-pub ahead of print
Date Deposited: 16 Feb 2012 15:26
Last Modified: 18 Apr 2017 00:25
Further Information:Google Scholar
URI: http://eprints.soton.ac.uk/id/eprint/210962

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