Application of a structured multifunctional reactor for the oxidation of a liquid organic feedstock
Application of a structured multifunctional reactor for the oxidation of a liquid organic feedstock
Experiments are performed in a structured packed bed reactor that has been developed for the selective oxidation of organic liquids to produce pharmaceutical products. Molecular oxygen is used as the oxidant, providing a “cleaner processing route”, than in established methods. The structured assembly consists of an integrated heat exchange system, a gas/liquid mixing zone, and provision for reactant injection. To illustrate the application, the selective oxidation of benzyl alcohol to benzaldehyde was studied. The reactor consisted of parallel reaction channels (10 cm long and square shaped) that were packed with Ru/Al2O3 (0.9 wt% Ru) catalyst particles. From experiments in three different sizes of channel: 2 mm × 2 mm, 3 mm × 3 mm, and 5 mm × 5 mm (at P = 8 bar, T = 388 K, with liquid and gas flows L = 3.2 kg m?2 s?1, G = 1.35 × 10?2 kg m?2 s?1), it was shown that in a short 10 cm length of channel, a product yield up to ca. 29% (with minimum 99.5% selectivity) could be obtained. Conversions were highest in the 3 mm × 3 mm channel. From the experiments with the reactor mounted both in horizontal and vertical planes, it was shown that gravitational influences are minor.
The choice of solvent was shown to affect the yield of benzaldehyde. The highest yield was with toluene; the application of dioxane/water mixture (70/30 by vol.) and N-methyl pyrrolidone (NMP) not only decreased the yield by factor 2, but NMP also caused deactivation of the catalyst.
Preliminary results are presented of work with Pt/C (Pt 3 wt%) catalyst.
bed reactor, liquid organic feedstock, oxygen
479-483
Plucinski, Pawel K.
d3730fd2-65ab-49bd-adb0-f56600012e10
Bavykin, Dmitry V.
1e9fabfc-d078-4585-876f-85ff33b7eed5
Kolaczkowski, Stan T.
b62d750a-c726-4fa1-bdcb-8418738c56bb
Lapkin, Alexei A.
e5550045-9bdc-4cca-873a-16c2f37a64c8
2005
Plucinski, Pawel K.
d3730fd2-65ab-49bd-adb0-f56600012e10
Bavykin, Dmitry V.
1e9fabfc-d078-4585-876f-85ff33b7eed5
Kolaczkowski, Stan T.
b62d750a-c726-4fa1-bdcb-8418738c56bb
Lapkin, Alexei A.
e5550045-9bdc-4cca-873a-16c2f37a64c8
Plucinski, Pawel K., Bavykin, Dmitry V., Kolaczkowski, Stan T. and Lapkin, Alexei A.
(2005)
Application of a structured multifunctional reactor for the oxidation of a liquid organic feedstock.
Catalysis Today, 105 (3-4), .
(doi:10.1016/j.cattod.2005.06.021).
Abstract
Experiments are performed in a structured packed bed reactor that has been developed for the selective oxidation of organic liquids to produce pharmaceutical products. Molecular oxygen is used as the oxidant, providing a “cleaner processing route”, than in established methods. The structured assembly consists of an integrated heat exchange system, a gas/liquid mixing zone, and provision for reactant injection. To illustrate the application, the selective oxidation of benzyl alcohol to benzaldehyde was studied. The reactor consisted of parallel reaction channels (10 cm long and square shaped) that were packed with Ru/Al2O3 (0.9 wt% Ru) catalyst particles. From experiments in three different sizes of channel: 2 mm × 2 mm, 3 mm × 3 mm, and 5 mm × 5 mm (at P = 8 bar, T = 388 K, with liquid and gas flows L = 3.2 kg m?2 s?1, G = 1.35 × 10?2 kg m?2 s?1), it was shown that in a short 10 cm length of channel, a product yield up to ca. 29% (with minimum 99.5% selectivity) could be obtained. Conversions were highest in the 3 mm × 3 mm channel. From the experiments with the reactor mounted both in horizontal and vertical planes, it was shown that gravitational influences are minor.
The choice of solvent was shown to affect the yield of benzaldehyde. The highest yield was with toluene; the application of dioxane/water mixture (70/30 by vol.) and N-methyl pyrrolidone (NMP) not only decreased the yield by factor 2, but NMP also caused deactivation of the catalyst.
Preliminary results are presented of work with Pt/C (Pt 3 wt%) catalyst.
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Published date: 2005
Additional Information:
2nd International Conference on Structured Catalysts and Reactors ICOSCAR-2 - 2nd International Conference on Structured Catalysts and Reactors ICOSCAR-2
Keywords:
bed reactor, liquid organic feedstock, oxygen
Identifiers
Local EPrints ID: 23614
URI: http://eprints.soton.ac.uk/id/eprint/23614
ISSN: 0920-5861
PURE UUID: 31d922ef-59eb-4c02-84b3-1b53b4d33c67
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Date deposited: 20 Mar 2006
Last modified: 15 Mar 2024 06:48
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Contributors
Author:
Pawel K. Plucinski
Author:
Stan T. Kolaczkowski
Author:
Alexei A. Lapkin
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