The University of Southampton
University of Southampton Institutional Repository

Numerical modelling of a microfluidic ultrasonic particle separator

Numerical modelling of a microfluidic ultrasonic particle separator
Numerical modelling of a microfluidic ultrasonic particle separator
Particles held in a fluid suspension and within an acoustic standing wave experience an acoustic radiation force. The force causes particles to move to the pressure nodes of the acoustic field creating a concentrate, contributing to the sensing of particles or cells. To predict the performance of devices relying on acoustic radiation forces and to assist with design, a simulation approach is used which combines several modelling techniques. Particle trajectories through the acoustic field and the resulting concentration profile are determined by resolving the forces experienced by particles numerically. This particle simulation model is further supported by more detailed analysis of the acoustic and fluid flow fields using finite element analysis and computational fluid dynamics, applicable to the microfluidic flow. These modelling techniques are applied to the simulation of a microfluidic ultrasonic particle separator, driven using a printed PZT transducer and relying on silicon and Pyrex etch fabrication. The device issues particle concentrated and clarified flow through two outlets, respectively. Test data taken from a fabricated device is used to evaluate the simulation approach which correlate well with eachother. The simulation approach is used successfully to redesign the acoustic and fluid geometry and to predict the influence of operating conditions.
acoustic separation, microfluidics, CFD, FEA, modelling
194-197
Townsend, R.J.
b9ed94bf-aceb-41fe-b50d-a4a2dc7fc98b
Hill, M.
0cda65c8-a70f-476f-b126-d2c4460a253e
Harris, N.R.
237cfdbd-86e4-4025-869c-c85136f14dfd
White, N.M.
c7be4c26-e419-4e5c-9420-09fc02e2ac9c
Beeby, S.P.
ba565001-2812-4300-89f1-fe5a437ecb0d
Townsend, R.J.
b9ed94bf-aceb-41fe-b50d-a4a2dc7fc98b
Hill, M.
0cda65c8-a70f-476f-b126-d2c4460a253e
Harris, N.R.
237cfdbd-86e4-4025-869c-c85136f14dfd
White, N.M.
c7be4c26-e419-4e5c-9420-09fc02e2ac9c
Beeby, S.P.
ba565001-2812-4300-89f1-fe5a437ecb0d

Townsend, R.J., Hill, M., Harris, N.R., White, N.M. and Beeby, S.P. (2005) Numerical modelling of a microfluidic ultrasonic particle separator. NSTI Nanotechnology Conference & Trade Show, Anaheim, USA. 07 - 11 May 2005. pp. 194-197 .

Record type: Conference or Workshop Item (Paper)

Abstract

Particles held in a fluid suspension and within an acoustic standing wave experience an acoustic radiation force. The force causes particles to move to the pressure nodes of the acoustic field creating a concentrate, contributing to the sensing of particles or cells. To predict the performance of devices relying on acoustic radiation forces and to assist with design, a simulation approach is used which combines several modelling techniques. Particle trajectories through the acoustic field and the resulting concentration profile are determined by resolving the forces experienced by particles numerically. This particle simulation model is further supported by more detailed analysis of the acoustic and fluid flow fields using finite element analysis and computational fluid dynamics, applicable to the microfluidic flow. These modelling techniques are applied to the simulation of a microfluidic ultrasonic particle separator, driven using a printed PZT transducer and relying on silicon and Pyrex etch fabrication. The device issues particle concentrated and clarified flow through two outlets, respectively. Test data taken from a fabricated device is used to evaluate the simulation approach which correlate well with eachother. The simulation approach is used successfully to redesign the acoustic and fluid geometry and to predict the influence of operating conditions.

This record has no associated files available for download.

More information

Published date: 2005
Venue - Dates: NSTI Nanotechnology Conference & Trade Show, Anaheim, USA, 2005-05-07 - 2005-05-11
Keywords: acoustic separation, microfluidics, CFD, FEA, modelling

Identifiers

Local EPrints ID: 23882
URI: http://eprints.soton.ac.uk/id/eprint/23882
PURE UUID: f78f4731-db44-4c20-8c8b-d4cf0aa70bb6
ORCID for M. Hill: ORCID iD orcid.org/0000-0001-6448-9448
ORCID for N.R. Harris: ORCID iD orcid.org/0000-0003-4122-2219
ORCID for N.M. White: ORCID iD orcid.org/0000-0003-1532-6452
ORCID for S.P. Beeby: ORCID iD orcid.org/0000-0002-0800-1759

Catalogue record

Date deposited: 29 Mar 2006
Last modified: 09 Jan 2022 02:45

Export record

Contributors

Author: R.J. Townsend
Author: M. Hill ORCID iD
Author: N.R. Harris ORCID iD
Author: N.M. White ORCID iD
Author: S.P. Beeby ORCID iD

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×