The University of Southampton
University of Southampton Institutional Repository

The association between diet and chronic obstructive pulmonary disease in subjects selected from general practice

Watson, L., Margetts, B., Howarth, P., Dorward, M., Thompson, R. and Little, P. (2002) The association between diet and chronic obstructive pulmonary disease in subjects selected from general practice European Respiratory Journal, 20, (2), pp. 313-318.

Record type: Article

Abstract

It is unclear why some smokers develop chronic obstructive pulmonary disease (COPD) whilst the majority do not. Antioxidants found in food may protect against lung tissue injury, but previous epidemiological studies are inconsistent and do not focus on those most at risk of COPD, namely smokers. This case-controlled study measured the difference in dietary intake between smokers and exsmokers with and without COPD.
Cases were patients >45 yrs of age with >10 pack-yrs of smoking, a forced expiratory volume in one second (FEV1)/forced vital capacity (FVC) of ?70% and a FEV1 of ?80% of predicted. Controls were patients >45 yrs of age with >10 pack-yrs of smoking, a FEV1/FVC of >70% and a FEV1 >80% pred. Data were collected using validated questionnaires. Logistic regression analysis for an unmatched case-controlled study was performed.
After controlling for other independent predictors of COPD, those with vegetable intake of ?1 portion·day–1 (93 g) were less likely to have COPD, as were those consuming ?1.5 portions·day–1 of fruit. This was not due to an overall reduction in food/calorie intake caused by the disease because: 1) adjusting for body mass index did not alter the estimates; 2) the effect was specific to fruit and vegetables, i.e. not other food groups; and 3) the estimates from incident cases were similar.
In conclusion, fruit and vegetable consumption is inversely associated with chronic obstructive pulmonary disease and may explain why some smokers do not develop chronic obstructive pulmonary disease.

PDF 313.pdf - Version of Record
Restricted to Repository staff only
Download (241kB)

More information

Published date: August 2002

Identifiers

Local EPrints ID: 24550
URI: http://eprints.soton.ac.uk/id/eprint/24550
ISSN: 0903-1936
PURE UUID: 7c5c35c0-3947-45ba-a980-f0a986e7863f

Catalogue record

Date deposited: 31 Mar 2006
Last modified: 17 Jul 2017 16:13

Export record

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×