Toward positional cloning with SNPs
Toward positional cloning with SNPs
Efficient methods are available for positional cloning of major genes by linkage and linkage disequilibrium (LD). The application of these methods to complex diseases is more demanding, but advances in sequencing the human genome, SNP discovery, high-throughput genotyping techniques, LD maps, and haplotype annotation are revolutionizing positional cloning of oligogenes for common multifactorial disease.
259-264
Morton, N.E.
c668e2be-074a-4a0a-a2ca-e8f51830ebb7
Collins, A.
7daa83eb-0b21-43b2-af1a-e38fb36e2a64
24 June 2002
Morton, N.E.
c668e2be-074a-4a0a-a2ca-e8f51830ebb7
Collins, A.
7daa83eb-0b21-43b2-af1a-e38fb36e2a64
Morton, N.E. and Collins, A.
(2002)
Toward positional cloning with SNPs.
Current Opinion in Molecular Therapeutics, 4 (3), .
Abstract
Efficient methods are available for positional cloning of major genes by linkage and linkage disequilibrium (LD). The application of these methods to complex diseases is more demanding, but advances in sequencing the human genome, SNP discovery, high-throughput genotyping techniques, LD maps, and haplotype annotation are revolutionizing positional cloning of oligogenes for common multifactorial disease.
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Published date: 24 June 2002
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Local EPrints ID: 24875
URI: http://eprints.soton.ac.uk/id/eprint/24875
ISSN: 1464-8431
PURE UUID: b9ad9320-d92a-4437-b37e-026cd7afab90
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Date deposited: 06 Apr 2006
Last modified: 23 Jul 2022 01:35
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Author:
N.E. Morton
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