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A retrospective collaboration on chromosome 5 by the International Consortium on Asthma Genetics (COAG)

A retrospective collaboration on chromosome 5 by the International Consortium on Asthma Genetics (COAG)
A retrospective collaboration on chromosome 5 by the International Consortium on Asthma Genetics (COAG)
Asthma is the most common chronic childhood disease in developed nations [ 1], affecting more than 155 million individuals. The cost of treating the disease in the USA alone approximates 6 billion dollars per annum [ 2]. Asthma is a complex disease that has proven extremely difficult to dissect genetically [ 3]. Considerable effort is currently being expended in attempts to detect genetic loci contributing to asthma susceptibility [ 4–7], with the ultimate goal of improving preventive strategies, diagnostic tools and therapies. However, no specific major gene exhibiting functional effects has been mapped to date.
0954-7894
152-154
Palmer, L.J.
b91d6236-22d5-405b-a653-bb831ae3002f
Lonjou, C.
81c7b685-b148-4d1e-a8e7-cbc75e8bc16a
Barnes, K.
16d4c700-62e1-49ba-83ea-84f0720f2405
Chen, H.
d30e2017-5be4-4a58-aacd-13fec55ae5f2
Cookson, W.O.C.M.
09698c30-d170-450d-a3b6-9732e1d15865
Deichmann, K.A.
180f71cd-9084-4c56-86b6-779f8433c115
Holloway, J.W.
4bbd77e6-c095-445d-a36b-a50a72f6fe1a
Laitinen, T.
d390e6e7-6202-42f3-a680-95f81c4ae300
Wjst, M.
c049b142-6252-4260-bbaa-2d1664d30090
Morton, N.E.
c668e2be-074a-4a0a-a2ca-e8f51830ebb7
Palmer, L.J.
b91d6236-22d5-405b-a653-bb831ae3002f
Lonjou, C.
81c7b685-b148-4d1e-a8e7-cbc75e8bc16a
Barnes, K.
16d4c700-62e1-49ba-83ea-84f0720f2405
Chen, H.
d30e2017-5be4-4a58-aacd-13fec55ae5f2
Cookson, W.O.C.M.
09698c30-d170-450d-a3b6-9732e1d15865
Deichmann, K.A.
180f71cd-9084-4c56-86b6-779f8433c115
Holloway, J.W.
4bbd77e6-c095-445d-a36b-a50a72f6fe1a
Laitinen, T.
d390e6e7-6202-42f3-a680-95f81c4ae300
Wjst, M.
c049b142-6252-4260-bbaa-2d1664d30090
Morton, N.E.
c668e2be-074a-4a0a-a2ca-e8f51830ebb7

Palmer, L.J., Lonjou, C., Barnes, K., Chen, H., Cookson, W.O.C.M., Deichmann, K.A., Holloway, J.W., Laitinen, T., Wjst, M. and Morton, N.E. (2001) A retrospective collaboration on chromosome 5 by the International Consortium on Asthma Genetics (COAG). Clinical & Experimental Allergy, 31 (1), 152-154. (doi:10.1046/j.1365-2222.2001.01040.x).

Record type: Article

Abstract

Asthma is the most common chronic childhood disease in developed nations [ 1], affecting more than 155 million individuals. The cost of treating the disease in the USA alone approximates 6 billion dollars per annum [ 2]. Asthma is a complex disease that has proven extremely difficult to dissect genetically [ 3]. Considerable effort is currently being expended in attempts to detect genetic loci contributing to asthma susceptibility [ 4–7], with the ultimate goal of improving preventive strategies, diagnostic tools and therapies. However, no specific major gene exhibiting functional effects has been mapped to date.

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Published date: 2001

Identifiers

Local EPrints ID: 24890
URI: http://eprints.soton.ac.uk/id/eprint/24890
ISSN: 0954-7894
PURE UUID: a9d5d082-43ec-46f8-be4e-f67058f4f885
ORCID for J.W. Holloway: ORCID iD orcid.org/0000-0001-9998-0464

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Date deposited: 06 Apr 2006
Last modified: 16 Mar 2024 02:57

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Contributors

Author: L.J. Palmer
Author: C. Lonjou
Author: K. Barnes
Author: H. Chen
Author: W.O.C.M. Cookson
Author: K.A. Deichmann
Author: J.W. Holloway ORCID iD
Author: T. Laitinen
Author: M. Wjst
Author: N.E. Morton

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