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Human embryonic germ cells for future neuronal replacement therapy

Human embryonic germ cells for future neuronal replacement therapy
Human embryonic germ cells for future neuronal replacement therapy
Stem cell therapy offers exciting potential for ambitious cellular replacement to treat human (h) disease, such as Parkinson's disease, Alzheimer's disease or even replacement of the cell death that follows thromboembolic stroke. The realisation of these treatments requires cellular resources possessing three essential characteristics: (i) self-renewal, (ii) the ability to differentiate to physiologically normal cell types and (iii) lack of tumourigenicity.
Here, we describe work on human embryonic germ cells (hEGCs), a population of cells alongside human embryonic stem cells (hESCs) with the potential to address these issues.
human, embryonic germ cell, primordial germ cell, stem cell, embryo, gonad
0361-9230
76-82
Turnpenny, Lee
31a2fb0f-b76a-490a-845d-f9d9a1501d3d
Cameron, Iain T.
f7595539-efa6-4687-b161-e1e93ff710f2
Spalluto, Cosma M.
6802ad50-bc38-404f-9a19-40916425183b
Hanley, Karen Piper
7047509f-9767-49e2-954f-2f8f5bbace1e
Wilson, David I.
1500fca1-7082-4271-95f4-691f1d1252a2
Hanley, Neil A.
bf03f7bb-f377-44fb-8344-0bb1ca8b2ef9
Turnpenny, Lee
31a2fb0f-b76a-490a-845d-f9d9a1501d3d
Cameron, Iain T.
f7595539-efa6-4687-b161-e1e93ff710f2
Spalluto, Cosma M.
6802ad50-bc38-404f-9a19-40916425183b
Hanley, Karen Piper
7047509f-9767-49e2-954f-2f8f5bbace1e
Wilson, David I.
1500fca1-7082-4271-95f4-691f1d1252a2
Hanley, Neil A.
bf03f7bb-f377-44fb-8344-0bb1ca8b2ef9

Turnpenny, Lee, Cameron, Iain T., Spalluto, Cosma M., Hanley, Karen Piper, Wilson, David I. and Hanley, Neil A. (2005) Human embryonic germ cells for future neuronal replacement therapy. Brain Research Bulletin, 68 (1-2), 76-82. (doi:10.1016/j.brainresbull.2005.08.014).

Record type: Article

Abstract

Stem cell therapy offers exciting potential for ambitious cellular replacement to treat human (h) disease, such as Parkinson's disease, Alzheimer's disease or even replacement of the cell death that follows thromboembolic stroke. The realisation of these treatments requires cellular resources possessing three essential characteristics: (i) self-renewal, (ii) the ability to differentiate to physiologically normal cell types and (iii) lack of tumourigenicity.
Here, we describe work on human embryonic germ cells (hEGCs), a population of cells alongside human embryonic stem cells (hESCs) with the potential to address these issues.

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More information

Published date: 15 December 2005
Additional Information: Proceedings of the 14th and 15th Meetings of the European Network for CNS Transplantation and Repair (NECTAR)
Related URLs:
Keywords: human, embryonic germ cell, primordial germ cell, stem cell, embryo, gonad

Identifiers

Local EPrints ID: 25003
URI: http://eprints.soton.ac.uk/id/eprint/25003
DOI: doi:10.1016/j.brainresbull.2005.08.014
ISSN: 0361-9230
PURE UUID: 4cc97da6-b21b-492f-a7df-98c4d0064017
ORCID for Iain T. Cameron: ORCID iD orcid.org/0000-0002-4875-267X
ORCID for Cosma M. Spalluto: ORCID iD orcid.org/0000-0001-7273-0844

Catalogue record

Date deposited: 04 Apr 2006
Last modified: 16 Mar 2024 03:24

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Contributors

Author: Lee Turnpenny
Author: Iain T. Cameron ORCID iD
Author: Cosma M. Spalluto ORCID iD
Author: Karen Piper Hanley
Author: David I. Wilson
Author: Neil A. Hanley

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