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An impulse response flow cytometric technique for blood cell characterisation - instrumentation and preliminary evaluation

An impulse response flow cytometric technique for blood cell characterisation - instrumentation and preliminary evaluation
An impulse response flow cytometric technique for blood cell characterisation - instrumentation and preliminary evaluation
A new technique for studying the properties of blood and other cells has been developed. It is based on measurement of the continuous electrical impedance spectrum of individual cells. The cellular impedance is obtained by applying an impulse and recording the impulse response while a stream of cells suspended in an electrolyte pass through a measurement aperture in a single file. Preliminary evaluation has demonstrated that the instrument prototype is capable of detecting characteristic spectra of different cell populations. This paper presents some theoretical aspects of the technique, an outline of the instrumentation design and preliminary experimental results
1881-1884
Liu, Y.
621975c3-5440-4f2c-b313-4e724228220d
Abel, E. W.
8e25fd4a-0483-4fa8-af03-eb74e13ea7ac
Belch, J. J. F.
6e93f18e-6325-4be8-8cdc-ec5bac46f82f
Chen, S.
9310a111-f79a-48b8-98c7-383ca93cbb80
Liu, Y.
621975c3-5440-4f2c-b313-4e724228220d
Abel, E. W.
8e25fd4a-0483-4fa8-af03-eb74e13ea7ac
Belch, J. J. F.
6e93f18e-6325-4be8-8cdc-ec5bac46f82f
Chen, S.
9310a111-f79a-48b8-98c7-383ca93cbb80

Liu, Y., Abel, E. W., Belch, J. J. F. and Chen, S. (1998) An impulse response flow cytometric technique for blood cell characterisation - instrumentation and preliminary evaluation. Proceedings of 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. pp. 1881-1884 .

Record type: Conference or Workshop Item (Other)

Abstract

A new technique for studying the properties of blood and other cells has been developed. It is based on measurement of the continuous electrical impedance spectrum of individual cells. The cellular impedance is obtained by applying an impulse and recording the impulse response while a stream of cells suspended in an electrolyte pass through a measurement aperture in a single file. Preliminary evaluation has demonstrated that the instrument prototype is capable of detecting characteristic spectra of different cell populations. This paper presents some theoretical aspects of the technique, an outline of the instrumentation design and preliminary experimental results

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c-1998-icem - Author's Original
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More information

Published date: 1998
Additional Information: 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society Organisation: IEEE Engineering in Medicine and Biology Society
Venue - Dates: Proceedings of 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 1998-01-01
Organisations: Southampton Wireless Group

Identifiers

Local EPrints ID: 251038
URI: http://eprints.soton.ac.uk/id/eprint/251038
PURE UUID: 911156d0-5e45-45d2-8cd6-6064c3a2c8b8

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Date deposited: 31 Mar 2000
Last modified: 17 Oct 2022 17:26

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Contributors

Author: Y. Liu
Author: E. W. Abel
Author: J. J. F. Belch
Author: S. Chen

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