Apoptosis in osteoarthritis [In special issue: Apoptosis in the Rheumatic Diseases]
Apoptosis in osteoarthritis [In special issue: Apoptosis in the Rheumatic Diseases]
Many studies have shown that apoptotic cell death occurs at an increased rate in osteoarthritic cartilage. Whichever type of cell death takes places in articular cartilage, it is important to prevent, because it is detrimental to articular cartilage maintenance. Thus, it is important to characterize events going on during cellular degeneration in more detail. Overall, physicians have reached a reasonable level of understanding of the extent of cell death occurring in the disease process, but they are still at an early stage in the understanding of the mechanisms underlying this process and the means of intervening in this facet of cartilage destruction.
639-653
Aigner, Thomas
73f9b1df-f827-40fb-b8f3-ccb7116720eb
Kim, Hyun A.
77b4bd50-74ef-40ea-9ba9-ebec20c2712a
Roach, Helmtrud I.
ca2ff1f4-1ada-4c56-9097-cd27ca4d199e
August 2004
Aigner, Thomas
73f9b1df-f827-40fb-b8f3-ccb7116720eb
Kim, Hyun A.
77b4bd50-74ef-40ea-9ba9-ebec20c2712a
Roach, Helmtrud I.
ca2ff1f4-1ada-4c56-9097-cd27ca4d199e
Aigner, Thomas, Kim, Hyun A. and Roach, Helmtrud I.
(2004)
Apoptosis in osteoarthritis [In special issue: Apoptosis in the Rheumatic Diseases].
Rheumatic Diseases Clinics of North America, 30 (3), .
(doi:10.1016/j.rdc.2004.04.002).
Abstract
Many studies have shown that apoptotic cell death occurs at an increased rate in osteoarthritic cartilage. Whichever type of cell death takes places in articular cartilage, it is important to prevent, because it is detrimental to articular cartilage maintenance. Thus, it is important to characterize events going on during cellular degeneration in more detail. Overall, physicians have reached a reasonable level of understanding of the extent of cell death occurring in the disease process, but they are still at an early stage in the understanding of the mechanisms underlying this process and the means of intervening in this facet of cartilage destruction.
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Published date: August 2004
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Local EPrints ID: 25182
URI: http://eprints.soton.ac.uk/id/eprint/25182
ISSN: 0889-857X
PURE UUID: f568e70a-e9e0-4931-92f9-2bc67a9c4ede
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Date deposited: 07 Apr 2006
Last modified: 15 Mar 2024 07:01
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Author:
Thomas Aigner
Author:
Hyun A. Kim
Author:
Helmtrud I. Roach
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