The malnourished baby and infant: relationship with type 2 diabetes
The malnourished baby and infant: relationship with type 2 diabetes
The growth of a baby is constrained by the nutrients and oxygen it receives from the mother. A mother's ability to nourish her baby is established during her own fetal life and by her nutritional experiences in childhood and adolescence, which determine her body size, composition and metabolism. Mother's diet in pregnancy has little effect on the baby's size at birth, but nevertheless programmes the baby. The fetus adapts to undernutrition by changing its metabolism, altering its production of hormones and the sensitivity of tissues to them, redistributing its blood flow, and slowing its growth rate. In some circumstances, the placenta may enlarge. Adaptations to undernutrition that occur during development permanently alter the structure and function of the body.
69-88
Barker, David J.P.
5c773838-b094-4ac1-999b-b5869717f243
2001
Barker, David J.P.
5c773838-b094-4ac1-999b-b5869717f243
Barker, David J.P.
(2001)
The malnourished baby and infant: relationship with type 2 diabetes.
British Medical Bulletin, 60 (1), .
(doi:10.1093/bmb/60.1.69).
Abstract
The growth of a baby is constrained by the nutrients and oxygen it receives from the mother. A mother's ability to nourish her baby is established during her own fetal life and by her nutritional experiences in childhood and adolescence, which determine her body size, composition and metabolism. Mother's diet in pregnancy has little effect on the baby's size at birth, but nevertheless programmes the baby. The fetus adapts to undernutrition by changing its metabolism, altering its production of hormones and the sensitivity of tissues to them, redistributing its blood flow, and slowing its growth rate. In some circumstances, the placenta may enlarge. Adaptations to undernutrition that occur during development permanently alter the structure and function of the body.
This record has no associated files available for download.
More information
Published date: 2001
Identifiers
Local EPrints ID: 25224
URI: http://eprints.soton.ac.uk/id/eprint/25224
ISSN: 0007-1420
PURE UUID: 3e8efd9d-5273-4f56-8adf-54e7c1133d35
Catalogue record
Date deposited: 07 Apr 2006
Last modified: 15 Mar 2024 07:01
Export record
Altmetrics
Contributors
Author:
David J.P. Barker
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics