Altered regional blood flow in the fetus: the origins of cardiovascular disease?
Altered regional blood flow in the fetus: the origins of cardiovascular disease?
A fetal response to hypoxia and other adverse influences is to redistribute blood flow in order to "spare" the brain. This, however, is associated with reduced growth of the liver and kidneys.
Conclusion: The long-term consequences of fetal redistribution of blood flow are unknown, but preliminary evidence suggests that there is an increased risk of coronary heart disease and hypertension in later life.
fetal blood flow, intrauterine growth retardation, cardiovascular disease
1559-1560
Barker, D. J. P.
963dd42f-0bfc-46f5-87b0-1ba13c545500
Hanson, M. A.
1952fad1-abc7-4284-a0bc-a7eb31f70a3f
2004
Barker, D. J. P.
963dd42f-0bfc-46f5-87b0-1ba13c545500
Hanson, M. A.
1952fad1-abc7-4284-a0bc-a7eb31f70a3f
Barker, D. J. P. and Hanson, M. A.
(2004)
Altered regional blood flow in the fetus: the origins of cardiovascular disease?
Acta Paediatrica, 93 (12), .
(doi:10.1080/08035250410024772).
Abstract
A fetal response to hypoxia and other adverse influences is to redistribute blood flow in order to "spare" the brain. This, however, is associated with reduced growth of the liver and kidneys.
Conclusion: The long-term consequences of fetal redistribution of blood flow are unknown, but preliminary evidence suggests that there is an increased risk of coronary heart disease and hypertension in later life.
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Published date: 2004
Keywords:
fetal blood flow, intrauterine growth retardation, cardiovascular disease
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Local EPrints ID: 25235
URI: http://eprints.soton.ac.uk/id/eprint/25235
ISSN: 0803-5253
PURE UUID: 0bec6425-4ab5-4d1d-97d5-ef19190ebd4e
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Date deposited: 07 Apr 2006
Last modified: 16 Mar 2024 03:17
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Author:
D. J. P. Barker
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