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Altered regional blood flow in the fetus: the origins of cardiovascular disease?

Altered regional blood flow in the fetus: the origins of cardiovascular disease?
Altered regional blood flow in the fetus: the origins of cardiovascular disease?
A fetal response to hypoxia and other adverse influences is to redistribute blood flow in order to "spare" the brain. This, however, is associated with reduced growth of the liver and kidneys.
Conclusion: The long-term consequences of fetal redistribution of blood flow are unknown, but preliminary evidence suggests that there is an increased risk of coronary heart disease and hypertension in later life.
fetal blood flow, intrauterine growth retardation, cardiovascular disease
0803-5253
1559-1560
Barker, D. J. P.
963dd42f-0bfc-46f5-87b0-1ba13c545500
Hanson, M. A.
1952fad1-abc7-4284-a0bc-a7eb31f70a3f
Barker, D. J. P.
963dd42f-0bfc-46f5-87b0-1ba13c545500
Hanson, M. A.
1952fad1-abc7-4284-a0bc-a7eb31f70a3f

Barker, D. J. P. and Hanson, M. A. (2004) Altered regional blood flow in the fetus: the origins of cardiovascular disease? Acta Paediatrica, 93 (12), 1559-1560. (doi:10.1080/08035250410024772).

Record type: Article

Abstract

A fetal response to hypoxia and other adverse influences is to redistribute blood flow in order to "spare" the brain. This, however, is associated with reduced growth of the liver and kidneys.
Conclusion: The long-term consequences of fetal redistribution of blood flow are unknown, but preliminary evidence suggests that there is an increased risk of coronary heart disease and hypertension in later life.

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More information

Published date: 2004
Keywords: fetal blood flow, intrauterine growth retardation, cardiovascular disease

Identifiers

Local EPrints ID: 25235
URI: http://eprints.soton.ac.uk/id/eprint/25235
ISSN: 0803-5253
PURE UUID: 0bec6425-4ab5-4d1d-97d5-ef19190ebd4e
ORCID for M. A. Hanson: ORCID iD orcid.org/0000-0002-6907-613X

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Date deposited: 07 Apr 2006
Last modified: 03 Dec 2019 01:53

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