The University of Southampton
University of Southampton Institutional Repository

High-density mapping of left atrial endocardial activation during sinus rhythm and coronary sinus pacing in patients with paroxysmal atrial fibrillation

High-density mapping of left atrial endocardial activation during sinus rhythm and coronary sinus pacing in patients with paroxysmal atrial fibrillation
High-density mapping of left atrial endocardial activation during sinus rhythm and coronary sinus pacing in patients with paroxysmal atrial fibrillation
Introduction: This study was designed to record global high-density maps of left atrial endocardial activation during sinus rhythm and coronary sinus pacing.
Method and Results: Noncontact mapping of the left atrium was performed in nine patients with paroxysmal atrial fibrillation undergoing pulmonary vein ablation procedures. High-density isopotential and isochronal activation maps were superimposed on three-dimensional reconstructions of left atrial geometry. Mapping was repeated during pacing from sites within the coronary sinus. Earliest left atrial endocardial activation occurred anterior to the right pulmonary veins in seven patients and on the anterosuperior septum in two patients. A line of conduction block was seen in the posterior wall and inferior septum in all patients. The direction of activation in the left atrial myocardium overlying the coronary sinus was different from the electrogram sequence in the coronary sinus catheter in 6 of 9 patients. During coronary sinus pacing, activation entered the left atrium a mean (SD) of 41 (13) ms after the pacing stimulus at a site 12 (10) mm from the endocardium overlying the pacing electrode. Lines of conduction block were present in the posterior wall and inferior septum.
Conclusion: In patients with paroxysmal atrial fibrillation, lines of conduction block are present in the left atrium during sinus rhythm and coronary sinus pacing. Electrograms recorded in the coronary sinus infrequently correspond to the direction of activation in the overlying left atrial myocardium.
1045-3873
1111-1117
Betts, Timothy R.
a9d90073-a54a-478c-81f0-39ecc5234047
Roberts, Paul R.
193431e8-f9d5-48d6-8f62-ed9052b2571d
Morgan, John M.
ac98099e-241d-4551-bc98-709f6dfc8680
Betts, Timothy R.
a9d90073-a54a-478c-81f0-39ecc5234047
Roberts, Paul R.
193431e8-f9d5-48d6-8f62-ed9052b2571d
Morgan, John M.
ac98099e-241d-4551-bc98-709f6dfc8680

Betts, Timothy R., Roberts, Paul R. and Morgan, John M. (2004) High-density mapping of left atrial endocardial activation during sinus rhythm and coronary sinus pacing in patients with paroxysmal atrial fibrillation. Journal of Cardiovascular Electrophysiology, 15 (10), 1111-1117.

Record type: Article

Abstract

Introduction: This study was designed to record global high-density maps of left atrial endocardial activation during sinus rhythm and coronary sinus pacing.
Method and Results: Noncontact mapping of the left atrium was performed in nine patients with paroxysmal atrial fibrillation undergoing pulmonary vein ablation procedures. High-density isopotential and isochronal activation maps were superimposed on three-dimensional reconstructions of left atrial geometry. Mapping was repeated during pacing from sites within the coronary sinus. Earliest left atrial endocardial activation occurred anterior to the right pulmonary veins in seven patients and on the anterosuperior septum in two patients. A line of conduction block was seen in the posterior wall and inferior septum in all patients. The direction of activation in the left atrial myocardium overlying the coronary sinus was different from the electrogram sequence in the coronary sinus catheter in 6 of 9 patients. During coronary sinus pacing, activation entered the left atrium a mean (SD) of 41 (13) ms after the pacing stimulus at a site 12 (10) mm from the endocardium overlying the pacing electrode. Lines of conduction block were present in the posterior wall and inferior septum.
Conclusion: In patients with paroxysmal atrial fibrillation, lines of conduction block are present in the left atrium during sinus rhythm and coronary sinus pacing. Electrograms recorded in the coronary sinus infrequently correspond to the direction of activation in the overlying left atrial myocardium.

Full text not available from this repository.

More information

Published date: 2004

Identifiers

Local EPrints ID: 25258
URI: https://eprints.soton.ac.uk/id/eprint/25258
ISSN: 1045-3873
PURE UUID: f5c947d2-55e0-4d7b-875b-f7799f8b09c8

Catalogue record

Date deposited: 06 Apr 2006
Last modified: 01 Nov 2017 12:48

Export record

Contributors

Author: Timothy R. Betts
Author: Paul R. Roberts
Author: John M. Morgan

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of https://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×