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Prevalence of diabetes and impaired glucose tolerance in patients with schizophrenia

Prevalence of diabetes and impaired glucose tolerance in patients with schizophrenia
Prevalence of diabetes and impaired glucose tolerance in patients with schizophrenia
Declaration of interest: C.B. is an employee of Eli Lilly & Co; R.H. has received educational grants and fees for lecturing and consultancy work from Eli Lilly & Co.
Background: A number of studies have examined the prevalence of diabetes mellitus and impaired glucose tolerance in general populations and in those with schizophrenia and other forms of serious mental illness.
Aims: To establish whether it is possible to describe accurately comparative rates of diabetes mellitus and impaired glucose tolerance in populations of people with schizophrenia and those without mental illness.
Method: Review of current literature.
Results: Research published in the pre-neuroleptic era suggested that people with severe mental illness were at increased risk of developing glycaemic abnormalities. Recent studies appear to confirm that the prevalence of diabetes and impaired glucose tolerance may be higher in people with schizophrenia than in the general population, and suggest that patients with schizophrenia have impaired glucose tolerance even before they begin treatment.
Conclusions: Schizophrenia may be a significant and independent risk factor for both diabetes and impaired glucose tolerance. Current data preclude precise estimates of the prevalence of these conditions among people with schizophrenia.
0007-1250
s67-s71
Bushe, Chris
cb7915e9-b24f-40f4-8d7c-02bb73274e93
Holt, Richard
d54202e1-fcf6-4a17-a320-9f32d7024393
Bushe, Chris
cb7915e9-b24f-40f4-8d7c-02bb73274e93
Holt, Richard
d54202e1-fcf6-4a17-a320-9f32d7024393

Bushe, Chris and Holt, Richard (2004) Prevalence of diabetes and impaired glucose tolerance in patients with schizophrenia. British Journal of Psychiatry, 184 (suppl. 47), s67-s71.

Record type: Article

Abstract

Declaration of interest: C.B. is an employee of Eli Lilly & Co; R.H. has received educational grants and fees for lecturing and consultancy work from Eli Lilly & Co.
Background: A number of studies have examined the prevalence of diabetes mellitus and impaired glucose tolerance in general populations and in those with schizophrenia and other forms of serious mental illness.
Aims: To establish whether it is possible to describe accurately comparative rates of diabetes mellitus and impaired glucose tolerance in populations of people with schizophrenia and those without mental illness.
Method: Review of current literature.
Results: Research published in the pre-neuroleptic era suggested that people with severe mental illness were at increased risk of developing glycaemic abnormalities. Recent studies appear to confirm that the prevalence of diabetes and impaired glucose tolerance may be higher in people with schizophrenia than in the general population, and suggest that patients with schizophrenia have impaired glucose tolerance even before they begin treatment.
Conclusions: Schizophrenia may be a significant and independent risk factor for both diabetes and impaired glucose tolerance. Current data preclude precise estimates of the prevalence of these conditions among people with schizophrenia.

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More information

Published date: 2004
Additional Information: Schizophrenia and diabetes 2003: an expert consensus meeting; Edited by T.G. Dinan

Identifiers

Local EPrints ID: 25305
URI: http://eprints.soton.ac.uk/id/eprint/25305
ISSN: 0007-1250
PURE UUID: 947aaa76-67ae-4f10-a1e7-fe5f44eb0078
ORCID for Richard Holt: ORCID iD orcid.org/0000-0001-8911-6744

Catalogue record

Date deposited: 07 Apr 2006
Last modified: 23 Jul 2022 01:48

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Contributors

Author: Chris Bushe
Author: Richard Holt ORCID iD

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