Interactions between peroxisome proliferator-activated receptor gene polymorphism and birth length influence risk for type 2 diabetes
Interactions between peroxisome proliferator-activated receptor gene polymorphism and birth length influence risk for type 2 diabetes
Type 2 diabetes has previously been shown to be associated with a small body size at birth, which is considered an indicator of the intrauterine environment. This inverse association has been observed between both birth weight and birth length (1,2). The peroxisome proliferator–activated receptor (PPAR) ?2 gene is associated with glucose and lipid metabolism and is therefore a major candidate gene for type 2 diabetes (3,4). We have previously reported that the effects of the Pro12Pro genotype of the PPAR ?2 gene on insulin.
2476-2477
Eriksson, Johan G.
eb96b1c5-af07-4a52-8a73-7541451d32cd
Osmond, Clive
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Lindi, Virpi
3866552e-b953-47fe-9345-e3b88d5a290f
Uusitupa, Matti
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Forsen, Tom
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Laakso, Markku
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Barker, David
0bfdcbdc-bc80-4c0f-9d07-ce3f9f82bc36
2003
Eriksson, Johan G.
eb96b1c5-af07-4a52-8a73-7541451d32cd
Osmond, Clive
2677bf85-494f-4a78-adf8-580e1b8acb81
Lindi, Virpi
3866552e-b953-47fe-9345-e3b88d5a290f
Uusitupa, Matti
7e87195e-7dfc-4887-91dc-146463d5f17e
Forsen, Tom
77245dbe-fc1f-4e6f-a2bb-6f1a77918cd2
Laakso, Markku
081d2484-2485-4783-9d51-5fe0a8db6715
Barker, David
0bfdcbdc-bc80-4c0f-9d07-ce3f9f82bc36
Eriksson, Johan G., Osmond, Clive, Lindi, Virpi, Uusitupa, Matti, Forsen, Tom, Laakso, Markku and Barker, David
(2003)
Interactions between peroxisome proliferator-activated receptor gene polymorphism and birth length influence risk for type 2 diabetes.
Diabetes Care, 26 (8), .
Abstract
Type 2 diabetes has previously been shown to be associated with a small body size at birth, which is considered an indicator of the intrauterine environment. This inverse association has been observed between both birth weight and birth length (1,2). The peroxisome proliferator–activated receptor (PPAR) ?2 gene is associated with glucose and lipid metabolism and is therefore a major candidate gene for type 2 diabetes (3,4). We have previously reported that the effects of the Pro12Pro genotype of the PPAR ?2 gene on insulin.
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Published date: 2003
Additional Information:
Letters: Observations
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Local EPrints ID: 25471
URI: http://eprints.soton.ac.uk/id/eprint/25471
ISSN: 1935-5548
PURE UUID: 57dc52ed-d82a-418f-a0bc-e7d67b826936
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Date deposited: 19 Apr 2006
Last modified: 23 Jul 2022 01:39
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Contributors
Author:
Johan G. Eriksson
Author:
Virpi Lindi
Author:
Matti Uusitupa
Author:
Tom Forsen
Author:
Markku Laakso
Author:
David Barker
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