Dietary intake of flavonoids and asthma in adults
Dietary intake of flavonoids and asthma in adults
Epidemiological studies have suggested that a high consumption of apples may protect against asthma and chronic obstructive pulmonary disease. This effect has been attributed to their high flavonoid content, but few studies have investigated the relationship between flavonoid intake and obstructive lung disease directly.
In a population-based, case-control study of 1,471 adults aged 16–50 yrs in London (UK), the present study examined whether dietary intake of catechins, flavonols and flavones was negatively associated with asthma, asthma severity and chronic sputum production. Asthma was defined by positive responses to a standard screening questionnaire in 1996 and information about usual diet was obtained by a food frequency questionnaire in 1997.
After controlling for potential confounders, dietary intake of these three flavonoid subclasses was not significantly associated with asthma, (odds ratio per quintile (95% confidence interval) = 0.94 (0.86–1.02); 1.00 (0.92–1.09); 0.98 (0.88 –1.08) for flavones, flavonols and total catechins, respectively) nor was it associated with asthma severity, or chronic sputum production.
In conclusion, no evidence was found for a protective effect of three major subclasses of dietary flavonoids on asthma. It is possible that other flavonoids or polyphenols present in apples may explain the protective effect of apples on obstructive lung disease.
antioxidants, apples, asthma, diet, flavonoids
449-452
Garcia, V.
3f783c6e-26be-4f88-b145-923be0b97c59
Arts, I.C.W.
df869c39-1106-4d11-9785-71929f3f3df2
Sterne, J.A.C.
7284734f-18f5-4119-8404-48a1dccaf0ea
Thompson, R.L.
1a394a6d-b006-4aec-b9be-b3e6c16fdb7b
Shaheen, S.O.
ae8e3194-c8a7-4f38-a71f-32da3ad0ea21
2005
Garcia, V.
3f783c6e-26be-4f88-b145-923be0b97c59
Arts, I.C.W.
df869c39-1106-4d11-9785-71929f3f3df2
Sterne, J.A.C.
7284734f-18f5-4119-8404-48a1dccaf0ea
Thompson, R.L.
1a394a6d-b006-4aec-b9be-b3e6c16fdb7b
Shaheen, S.O.
ae8e3194-c8a7-4f38-a71f-32da3ad0ea21
Garcia, V., Arts, I.C.W., Sterne, J.A.C., Thompson, R.L. and Shaheen, S.O.
(2005)
Dietary intake of flavonoids and asthma in adults.
European Respiratory Journal, 26 (3), .
Abstract
Epidemiological studies have suggested that a high consumption of apples may protect against asthma and chronic obstructive pulmonary disease. This effect has been attributed to their high flavonoid content, but few studies have investigated the relationship between flavonoid intake and obstructive lung disease directly.
In a population-based, case-control study of 1,471 adults aged 16–50 yrs in London (UK), the present study examined whether dietary intake of catechins, flavonols and flavones was negatively associated with asthma, asthma severity and chronic sputum production. Asthma was defined by positive responses to a standard screening questionnaire in 1996 and information about usual diet was obtained by a food frequency questionnaire in 1997.
After controlling for potential confounders, dietary intake of these three flavonoid subclasses was not significantly associated with asthma, (odds ratio per quintile (95% confidence interval) = 0.94 (0.86–1.02); 1.00 (0.92–1.09); 0.98 (0.88 –1.08) for flavones, flavonols and total catechins, respectively) nor was it associated with asthma severity, or chronic sputum production.
In conclusion, no evidence was found for a protective effect of three major subclasses of dietary flavonoids on asthma. It is possible that other flavonoids or polyphenols present in apples may explain the protective effect of apples on obstructive lung disease.
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Published date: 2005
Keywords:
antioxidants, apples, asthma, diet, flavonoids
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Local EPrints ID: 25526
URI: http://eprints.soton.ac.uk/id/eprint/25526
ISSN: 0903-1936
PURE UUID: 94f8ec70-6a47-4070-9b78-34711fbdd756
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Date deposited: 10 Apr 2006
Last modified: 08 Jan 2022 09:52
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Contributors
Author:
V. Garcia
Author:
I.C.W. Arts
Author:
J.A.C. Sterne
Author:
R.L. Thompson
Author:
S.O. Shaheen
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