Living with the past: evolution, development, and patterns of disease
Living with the past: evolution, development, and patterns of disease
Epidemiological observations have led to the hypothesis that the risk of developing some chronic noncommunicable diseases in adulthood is influenced not only by genetic and adult life-style factors but also by environmental factors acting in early life. Research in evolutionary biology, developmental biology, and animal and human physiology provides support for this idea and suggests that environmental processes influencing the propensity to disease in adulthood operate during the periconceptual, fetal, and infant phases of life. This "developmental origins of health and disease" concept may have important biological, medical, and socioeconomic implications.
1733-1736
Gluckman, Peter D.
ef2e8b92-0b76-4a12-bd7c-01b0674f94d3
Hanson, Mark A.
1952fad1-abc7-4284-a0bc-a7eb31f70a3f
2004
Gluckman, Peter D.
ef2e8b92-0b76-4a12-bd7c-01b0674f94d3
Hanson, Mark A.
1952fad1-abc7-4284-a0bc-a7eb31f70a3f
Gluckman, Peter D. and Hanson, Mark A.
(2004)
Living with the past: evolution, development, and patterns of disease.
Science, 305 (5691), .
(doi:10.1126/science.1095292).
Abstract
Epidemiological observations have led to the hypothesis that the risk of developing some chronic noncommunicable diseases in adulthood is influenced not only by genetic and adult life-style factors but also by environmental factors acting in early life. Research in evolutionary biology, developmental biology, and animal and human physiology provides support for this idea and suggests that environmental processes influencing the propensity to disease in adulthood operate during the periconceptual, fetal, and infant phases of life. This "developmental origins of health and disease" concept may have important biological, medical, and socioeconomic implications.
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Published date: 2004
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Review article
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Local EPrints ID: 25540
URI: http://eprints.soton.ac.uk/id/eprint/25540
ISSN: 0036-8075
PURE UUID: 0f2f4355-aed9-4e0d-a8b6-0b79ee0a3864
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Date deposited: 07 Apr 2006
Last modified: 16 Mar 2024 03:17
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Peter D. Gluckman
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