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Determinants of fracture risk in osteoporosis

Determinants of fracture risk in osteoporosis
Determinants of fracture risk in osteoporosis
Osteoporosis is a major public health issue, with fragility fractures of the hip, vertebrae, and distal radius considered the most important consequences. These lead to increased morbidity, mortality, hospital care, and dependency. The risk factors for the development of fragility fractures are numerous and involve genetic and environmental influences, as well as an interaction between the two. In this review, the recent literature examining genetic factors, possible candidate genes, the evolving area of intrauterine fetal programming, and anthropometric and environmental factors will be reviewed.
1523-3774
75-81
Harvey, Nicholas
6a655234-2597-4d42-8dba-0ffd7e6bfa39
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Harvey, Nicholas
6a655234-2597-4d42-8dba-0ffd7e6bfa39
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6

Harvey, Nicholas and Cooper, Cyrus (2003) Determinants of fracture risk in osteoporosis. Current Rheumatology Reports, 5 (1), 75-81.

Record type: Article

Abstract

Osteoporosis is a major public health issue, with fragility fractures of the hip, vertebrae, and distal radius considered the most important consequences. These lead to increased morbidity, mortality, hospital care, and dependency. The risk factors for the development of fragility fractures are numerous and involve genetic and environmental influences, as well as an interaction between the two. In this review, the recent literature examining genetic factors, possible candidate genes, the evolving area of intrauterine fetal programming, and anthropometric and environmental factors will be reviewed.

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Published date: 2003
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Identifiers

Local EPrints ID: 25591
URI: http://eprints.soton.ac.uk/id/eprint/25591
ISSN: 1523-3774
PURE UUID: 27275c3d-d093-4f3e-bdee-2f46df2faa5b
ORCID for Cyrus Cooper: ORCID iD orcid.org/0000-0003-3510-0709

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Date deposited: 11 Apr 2006
Last modified: 18 Mar 2024 02:44

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Contributors

Author: Nicholas Harvey
Author: Cyrus Cooper ORCID iD

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