The metabolic effects of growth hormone
The metabolic effects of growth hormone
Growth hormone has major biological actions that persist into adulthood and are important for normal wellbeing. GH interacts with insulin to regulate fuel supplies between feeding and fasting. While GH promotes protein anabolism and nitrogen retention, its catabolic actions in adipose tissue have led to the concept that it is a partitioning agent for nutrients. A role for the GH-IGF axis in normal glucose homeostasis has been established and it is clear that GH is involved in body fluid balance, bone and calcium metabolism as well as energy expenditure. The importance of these actions can be finally appreciated by examining the excess morbidity and mortality seen in individuals with GH deficiency.
protein metabolism, lipid metabolism, glucose metabolism, fluid balance, bone turnover, growth hormone, metabolism
11-17
Holt, R.I.G.
d54202e1-fcf6-4a17-a320-9f32d7024393
2004
Holt, R.I.G.
d54202e1-fcf6-4a17-a320-9f32d7024393
Holt, R.I.G.
(2004)
The metabolic effects of growth hormone.
CME Bulletin Endocrinology and Diabetes, 5 (1), .
Abstract
Growth hormone has major biological actions that persist into adulthood and are important for normal wellbeing. GH interacts with insulin to regulate fuel supplies between feeding and fasting. While GH promotes protein anabolism and nitrogen retention, its catabolic actions in adipose tissue have led to the concept that it is a partitioning agent for nutrients. A role for the GH-IGF axis in normal glucose homeostasis has been established and it is clear that GH is involved in body fluid balance, bone and calcium metabolism as well as energy expenditure. The importance of these actions can be finally appreciated by examining the excess morbidity and mortality seen in individuals with GH deficiency.
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Published date: 2004
Keywords:
protein metabolism, lipid metabolism, glucose metabolism, fluid balance, bone turnover, growth hormone, metabolism
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Local EPrints ID: 25631
URI: http://eprints.soton.ac.uk/id/eprint/25631
ISSN: 1367-8973
PURE UUID: 6014c5a9-0477-424e-9eb0-848da6e431a5
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Date deposited: 11 Apr 2006
Last modified: 09 Jan 2022 03:05
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