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Evaluation of body weight as a predictive factor for transvenous ventricular defibrillation characteristics

Paisey, J.R., Betts, T., Allen, S., Morgan, J.M. and Roberts, P.R. (2004) Evaluation of body weight as a predictive factor for transvenous ventricular defibrillation characteristics Europace, 6, (1), pp. 21-24. (doi:10.1016/j.eupc.2003.09.005).

Record type: Article

Abstract

Aims
To investigate the correlation between body weight and defibrillation threshold (DFT) for transvenous lead systems using a porcine model.
Methods and results
Twenty-eight pigs were anaesthetised and DFTs assessed in single and dual coil configurations using a four-reversal binary search method. DFT was correlated with body weight in the RV ? Can and RV ? SVC + Can configurations. A Pearson correlation coefficient and a two-sided p-value were calculated. A positive correlation exists between body weight and DFT in RV ? Can (, ) and RV ? SVC + Can (, ).
Conclusion
There is a significant correlation between body weight and DFT in swine. This tends to be greater in the two-electrode than in the three-electrode configuration. With these and previous human observations, one may predict a higher DFT in heavy individuals and make appropriate procedural adjustments.

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More information

Published date: 2004
Additional Information: Review
Keywords: implantable cardioverter defibrillator, defibrillation threshold, ventricular arrhythmia, fibrillation, body weight

Identifiers

Local EPrints ID: 25871
URI: http://eprints.soton.ac.uk/id/eprint/25871
ISSN: 1099-5129
PURE UUID: 794ea564-6958-490f-a74d-95e738f93b9d

Catalogue record

Date deposited: 21 Apr 2006
Last modified: 17 Jul 2017 16:09

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Contributors

Author: J.R. Paisey
Author: T. Betts
Author: S. Allen
Author: J.M. Morgan
Author: P.R. Roberts

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