Scouting Enzyme Behavior
Scouting Enzyme Behavior
Experimental exploration of enzymatic response in a multi-dimensional context faces the challenge of an explosive number of possible milieu conditions. We address this problem with an evolutionary search strategy that scouts the physiochemical milieu space for unanticipated enzyme behavior and rewards the discovery of experimental conditions that yield surprises.
scientific discovery, biochemistry, systems biology, malate dehydrogenase, autonomous experimentation, evolution, surprise
0-7803-7278-6
CEC19-24
Matsumaru, N.
8053c166-6cd3-4803-a178-e7cf35c231b0
Colombano, S.
687da317-944a-4134-a5e2-a8d77788cf4d
Zauner, K.-P.
c8b22dbd-10e6-43d8-813b-0766f985cc97
2002
Matsumaru, N.
8053c166-6cd3-4803-a178-e7cf35c231b0
Colombano, S.
687da317-944a-4134-a5e2-a8d77788cf4d
Zauner, K.-P.
c8b22dbd-10e6-43d8-813b-0766f985cc97
Matsumaru, N., Colombano, S. and Zauner, K.-P.
(2002)
Scouting Enzyme Behavior.
Fogel, D. B., El-Sharkawi, M. A., Yao, X., Greenwood, G., Iba, H., Marrow, P. and Shackleton, M.
(eds.)
In Proceedings of the 2002 World Congress on Computational Intelligence, May 12-17 Honolulu, Hawaii.
IEEE.
.
Record type:
Conference or Workshop Item
(Paper)
Abstract
Experimental exploration of enzymatic response in a multi-dimensional context faces the challenge of an explosive number of possible milieu conditions. We address this problem with an evolutionary search strategy that scouts the physiochemical milieu space for unanticipated enzyme behavior and rewards the discovery of experimental conditions that yield surprises.
Text
MatsumaruN02ScoutingEnz.pdf
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More information
Published date: 2002
Keywords:
scientific discovery, biochemistry, systems biology, malate dehydrogenase, autonomous experimentation, evolution, surprise
Organisations:
Agents, Interactions & Complexity
Identifiers
Local EPrints ID: 259133
URI: http://eprints.soton.ac.uk/id/eprint/259133
ISBN: 0-7803-7278-6
PURE UUID: c88247d4-8b60-4009-b6f4-25253c25d9b6
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Date deposited: 12 Mar 2004
Last modified: 14 Mar 2024 06:19
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Contributors
Author:
N. Matsumaru
Author:
S. Colombano
Author:
K.-P. Zauner
Editor:
D. B. Fogel
Editor:
M. A. El-Sharkawi
Editor:
X. Yao
Editor:
G. Greenwood
Editor:
H. Iba
Editor:
P. Marrow
Editor:
M. Shackleton
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