The University of Southampton
University of Southampton Institutional Repository

Scouting Enzyme Behavior

Scouting Enzyme Behavior
Scouting Enzyme Behavior
Experimental exploration of enzymatic response in a multi-dimensional context faces the challenge of an explosive number of possible milieu conditions. We address this problem with an evolutionary search strategy that scouts the physiochemical milieu space for unanticipated enzyme behavior and rewards the discovery of experimental conditions that yield surprises.
scientific discovery, biochemistry, systems biology, malate dehydrogenase, autonomous experimentation, evolution, surprise
0-7803-7278-6
CEC19-24
IEEE, Piscataway, NJ
Matsumaru, N.
8053c166-6cd3-4803-a178-e7cf35c231b0
Colombano, S.
687da317-944a-4134-a5e2-a8d77788cf4d
Zauner, K.-P.
c8b22dbd-10e6-43d8-813b-0766f985cc97
Fogel, D. B.
El-Sharkawi, M. A.
Yao, X.
Greenwood, G.
Iba, H.
Marrow, P.
Shackleton, M.
Matsumaru, N.
8053c166-6cd3-4803-a178-e7cf35c231b0
Colombano, S.
687da317-944a-4134-a5e2-a8d77788cf4d
Zauner, K.-P.
c8b22dbd-10e6-43d8-813b-0766f985cc97
Fogel, D. B.
El-Sharkawi, M. A.
Yao, X.
Greenwood, G.
Iba, H.
Marrow, P.
Shackleton, M.

Matsumaru, N., Colombano, S. and Zauner, K.-P. (2002) Scouting Enzyme Behavior. Fogel, D. B., El-Sharkawi, M. A., Yao, X., Greenwood, G., Iba, H., Marrow, P. and Shackleton, M. (eds.) In Proceedings of the 2002 World Congress on Computational Intelligence, May 12-17 Honolulu, Hawaii. IEEE, Piscataway, NJ. CEC19-24 .

Record type: Conference or Workshop Item (Paper)

Abstract

Experimental exploration of enzymatic response in a multi-dimensional context faces the challenge of an explosive number of possible milieu conditions. We address this problem with an evolutionary search strategy that scouts the physiochemical milieu space for unanticipated enzyme behavior and rewards the discovery of experimental conditions that yield surprises.

Text
MatsumaruN02ScoutingEnz.pdf - Other
Download (561kB)

More information

Published date: 2002
Keywords: scientific discovery, biochemistry, systems biology, malate dehydrogenase, autonomous experimentation, evolution, surprise
Organisations: Agents, Interactions & Complexity

Identifiers

Local EPrints ID: 259133
URI: http://eprints.soton.ac.uk/id/eprint/259133
ISBN: 0-7803-7278-6
PURE UUID: c88247d4-8b60-4009-b6f4-25253c25d9b6

Catalogue record

Date deposited: 12 Mar 2004
Last modified: 02 Dec 2019 21:09

Export record

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×