The University of Southampton
University of Southampton Institutional Repository

Some effects of sustained compression on ulcerated tissues

Some effects of sustained compression on ulcerated tissues
Some effects of sustained compression on ulcerated tissues
Sustained leg compression is the first line of treatment for patients with chronic venous ulcers. The success rates of this treatment vary, and the mode(s) of action are not well understood. In this study, tissue oxygen tension (TcPO2), surface pH, and reactive hyperemia measurements were made to observe changes associated with sustained compression in patients with chronic venous ulcers. Patients with chronic venous ulcers (n = 20, 13 F, 7 M, median age 65.5 years, median ulcer size 13.9 cm2) were assigned to the same treatment, wound dressings, and 4-layer bandaging during a 24-week period. Duplex ultrasound, venous refilling time, skin tissue oxygen, and ulcer surface pH were measured at defined time points. Ulcer areas were calculated from contour traces done at regular dressing changes. The difference between ulcer surface pH and control values measured proximally on the same leg diminished with healing (p = 0.02), which occurred despite the evidence of deep venous reflux. Ulcers with smaller initial areas healed quicker (p = 0.003). A greater likelihood of healing was observed in women (p = 0.017). Sustained compression may potentiate healing by acting on the microcirculation in ulcerated tissues.
0003-3197
451-456
Roberts, Geoff
7e8d4840-5875-4207-9734-d0ebc16f860c
Hammad, Lina
2f19763a-80f9-4f79-941d-dab5916d25f2
Collins, Carol
0bd6d540-7547-45f6-90a3-85fb663eee9b
Shearman, Cliff
cf4d6317-f54d-4ab3-ba49-c6797897bbcf
Mani, Raj
4c2dd177-1f73-4000-ba80-8523a50d1935
Roberts, Geoff
7e8d4840-5875-4207-9734-d0ebc16f860c
Hammad, Lina
2f19763a-80f9-4f79-941d-dab5916d25f2
Collins, Carol
0bd6d540-7547-45f6-90a3-85fb663eee9b
Shearman, Cliff
cf4d6317-f54d-4ab3-ba49-c6797897bbcf
Mani, Raj
4c2dd177-1f73-4000-ba80-8523a50d1935

Roberts, Geoff, Hammad, Lina, Collins, Carol, Shearman, Cliff and Mani, Raj (2002) Some effects of sustained compression on ulcerated tissues. Angiology, 53 (4), 451-456. (doi:10.1177/000331970205300412).

Record type: Article

Abstract

Sustained leg compression is the first line of treatment for patients with chronic venous ulcers. The success rates of this treatment vary, and the mode(s) of action are not well understood. In this study, tissue oxygen tension (TcPO2), surface pH, and reactive hyperemia measurements were made to observe changes associated with sustained compression in patients with chronic venous ulcers. Patients with chronic venous ulcers (n = 20, 13 F, 7 M, median age 65.5 years, median ulcer size 13.9 cm2) were assigned to the same treatment, wound dressings, and 4-layer bandaging during a 24-week period. Duplex ultrasound, venous refilling time, skin tissue oxygen, and ulcer surface pH were measured at defined time points. Ulcer areas were calculated from contour traces done at regular dressing changes. The difference between ulcer surface pH and control values measured proximally on the same leg diminished with healing (p = 0.02), which occurred despite the evidence of deep venous reflux. Ulcers with smaller initial areas healed quicker (p = 0.003). A greater likelihood of healing was observed in women (p = 0.017). Sustained compression may potentiate healing by acting on the microcirculation in ulcerated tissues.

This record has no associated files available for download.

More information

Published date: July 2002

Identifiers

Local EPrints ID: 25941
URI: http://eprints.soton.ac.uk/id/eprint/25941
ISSN: 0003-3197
PURE UUID: 790e27d1-1799-450a-ae3c-a8ec09fd231c

Catalogue record

Date deposited: 11 Apr 2006
Last modified: 15 Mar 2024 07:06

Export record

Altmetrics

Contributors

Author: Geoff Roberts
Author: Lina Hammad
Author: Carol Collins
Author: Cliff Shearman
Author: Raj Mani

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×