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Infection and prematurity and the role of preventive strategies

Infection and prematurity and the role of preventive strategies
Infection and prematurity and the role of preventive strategies
This article reviews the role of infection in spontaneous premature parturition, the pathways of ascending intrauterine infection, microbiology, and the frequency of intra-amniotic infection in obstetrical complications leading to premature delivery. The evidence that infection is causally linked to premature birth is critically examined, as is the relationship between urogenital tract infection/colonization with microorganisms and the risk of preterm birth. The effect of antibiotic administration in perinatal outcome in patients with preterm labor and intact membranes, preterm premature rupture of membranes, asymptomatic bacteriuria, Group B streptococcus and genital mycoplasmas of the lower genital tract, and bacterial vaginosis are critically examined.
infection, prematurity, asymptomatic bacteriuria, bacterial vaginosis, antibiotic treatment in pregnancy
1744-165X
259-274
Romero, Roberto
8b509793-372c-460e-9aa1-5a029e0e0c59
Espinoza, Jimmy
397e9980-13de-434e-a16f-dff3b801a087
Chaiworapongsa, Tinnakorn
15f72a08-0e49-4964-8de9-771b5647ad41
Kalache, Karim
e54bb068-f873-48f3-8ee1-91daf8317a90
Romero, Roberto
8b509793-372c-460e-9aa1-5a029e0e0c59
Espinoza, Jimmy
397e9980-13de-434e-a16f-dff3b801a087
Chaiworapongsa, Tinnakorn
15f72a08-0e49-4964-8de9-771b5647ad41
Kalache, Karim
e54bb068-f873-48f3-8ee1-91daf8317a90

Romero, Roberto, Espinoza, Jimmy, Chaiworapongsa, Tinnakorn and Kalache, Karim (2002) Infection and prematurity and the role of preventive strategies. Seminars in Fetal and Neonatal Medicine, 7 (4), 259-274. (doi:10.1053/siny.2002.0121).

Record type: Article

Abstract

This article reviews the role of infection in spontaneous premature parturition, the pathways of ascending intrauterine infection, microbiology, and the frequency of intra-amniotic infection in obstetrical complications leading to premature delivery. The evidence that infection is causally linked to premature birth is critically examined, as is the relationship between urogenital tract infection/colonization with microorganisms and the risk of preterm birth. The effect of antibiotic administration in perinatal outcome in patients with preterm labor and intact membranes, preterm premature rupture of membranes, asymptomatic bacteriuria, Group B streptococcus and genital mycoplasmas of the lower genital tract, and bacterial vaginosis are critically examined.

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More information

Published date: 2002
Keywords: infection, prematurity, asymptomatic bacteriuria, bacterial vaginosis, antibiotic treatment in pregnancy

Identifiers

Local EPrints ID: 25948
URI: http://eprints.soton.ac.uk/id/eprint/25948
ISSN: 1744-165X
PURE UUID: 61a270c5-dbd4-4f72-99f2-9c32e2ca065f

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Date deposited: 11 Apr 2006
Last modified: 15 Mar 2024 07:06

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Contributors

Author: Roberto Romero
Author: Jimmy Espinoza
Author: Tinnakorn Chaiworapongsa
Author: Karim Kalache

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