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Infection and prematurity and the role of preventive strategies

Romero, Roberto, Espinoza, Jimmy, Chaiworapongsa, Tinnakorn and Kalache, Karim (2002) Infection and prematurity and the role of preventive strategies Seminars in fetal and neonatal medicine, 7, (4), pp. 259-274. (doi:10.1053/siny.2002.0121).

Record type: Article


This article reviews the role of infection in spontaneous premature parturition, the pathways of ascending intrauterine infection, microbiology, and the frequency of intra-amniotic infection in obstetrical complications leading to premature delivery. The evidence that infection is causally linked to premature birth is critically examined, as is the relationship between urogenital tract infection/colonization with microorganisms and the risk of preterm birth. The effect of antibiotic administration in perinatal outcome in patients with preterm labor and intact membranes, preterm premature rupture of membranes, asymptomatic bacteriuria, Group B streptococcus and genital mycoplasmas of the lower genital tract, and bacterial vaginosis are critically examined.

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Published date: 2002
Keywords: infection, prematurity, asymptomatic bacteriuria, bacterial vaginosis, antibiotic treatment in pregnancy


Local EPrints ID: 25948
ISSN: 1744-165X
PURE UUID: 61a270c5-dbd4-4f72-99f2-9c32e2ca065f

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Date deposited: 11 Apr 2006
Last modified: 17 Jul 2017 16:09

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Author: Roberto Romero
Author: Jimmy Espinoza
Author: Tinnakorn Chaiworapongsa
Author: Karim Kalache

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