Delivery systems for bone growth factors - the new players in skeletal regeneration
Delivery systems for bone growth factors - the new players in skeletal regeneration
Given the challenge of an increasing elderly population, the ability to repair and regenerate traumatised or lost tissue is a major clinical and socio-economic need. Pivotal in this process will be the ability to deliver appropriate growth factors in the repair cascade in a temporal and tightly regulated sequence using appropriately designed matrices and release technologies within a tissue engineering strategy. This review outlines the current concepts and challenges in growth factor delivery for skeletal regeneration and the potential of novel delivery matrices and biotechnologies to influence the healthcare of an increasing ageing population.
415-427
Rose, F.R.A.J.
21b865f1-951e-42e1-8748-e43af6cf754e
Hou, Q.
b47013fe-ee6d-40bb-a1df-19a4d48f0bc7
Oreffo, R.O.C.
ff9fff72-6855-4d0f-bfb2-311d0e8f3778
2004
Rose, F.R.A.J.
21b865f1-951e-42e1-8748-e43af6cf754e
Hou, Q.
b47013fe-ee6d-40bb-a1df-19a4d48f0bc7
Oreffo, R.O.C.
ff9fff72-6855-4d0f-bfb2-311d0e8f3778
Rose, F.R.A.J., Hou, Q. and Oreffo, R.O.C.
(2004)
Delivery systems for bone growth factors - the new players in skeletal regeneration.
Journal of Pharmacy and Pharmacology, 56 (4), .
(doi:10.1211/0022357).
Abstract
Given the challenge of an increasing elderly population, the ability to repair and regenerate traumatised or lost tissue is a major clinical and socio-economic need. Pivotal in this process will be the ability to deliver appropriate growth factors in the repair cascade in a temporal and tightly regulated sequence using appropriately designed matrices and release technologies within a tissue engineering strategy. This review outlines the current concepts and challenges in growth factor delivery for skeletal regeneration and the potential of novel delivery matrices and biotechnologies to influence the healthcare of an increasing ageing population.
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Published date: 2004
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Review Article
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Local EPrints ID: 25952
URI: http://eprints.soton.ac.uk/id/eprint/25952
ISSN: 0022-3573
PURE UUID: d3e840eb-7864-46f1-ad62-9dd94188bef0
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Date deposited: 12 Apr 2006
Last modified: 16 Mar 2024 03:11
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Author:
F.R.A.J. Rose
Author:
Q. Hou
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